SCHEMBL3199567

SCHEMBL3199567

CC(=O)c1nc2ccccc2cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.45
KDM4E B2RXH2 5/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
MAPT P10636 3/20 0.43
GLA P06280 2/20 0.43
HPGD P15428 2/20 0.43
ACHE P22303 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
MAPK1 P28482 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
GAA P10253 1/20 0.42
STAT3 P40763 1/20 0.42
IKBKB O14920 1/20 0.41
MAP4K4 O95819 1/20 0.41
CSNK1G2 P78368 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
MKNK2 Q9HBH9 1/20 0.41
MAP4K5 Q9Y4K4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2777042 0.84 ALDH1A1 (0.59) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL25359333 0.82 IKBKB (0.53) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL30832203 0.82 IKBKB (0.53) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL30693766 0.81 KDM4E (0.50) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL27632420 0.81 KDM4E (0.50) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL27828993 0.80 IKBKB (0.50) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL2975427 0.80 KDM4E (0.56) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL27822691 0.80 TDP1 (0.52) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL28327975 0.79 CNR2 (0.51) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL9632211 0.77 ALDH1A1 (0.51) ALDH1A1KDM4EKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100035997-A1 KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES BROADLEY KENNETH N 2010-02-11 US claimed
US-20100035997-A1 KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES BROADLEY KENNETH N 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035997-A1 KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES KIT, TEKT1, CUTA ALDH1A1 740/4885KDM4E 2358/4885KMT2A 1310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.