Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28327975 | 0.84 | CNR2 (0.51) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL25359333 | 0.84 | IKBKB (0.53) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL30832203 | 0.84 | IKBKB (0.53) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3199567 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL30556744 | 0.80 | DYRK1A (0.47) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8802100 | 0.80 | DYRK1A (0.47) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL18795093 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30693766 | 0.80 | KDM4E (0.50) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL27632420 | 0.80 | KDM4E (0.50) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL70017 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141883-A1 | COMPOUNDS THAT MODULATE AUTOIMMUNITY AND METHODS OF USING THE SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2010-12-09 | — | — | WO | claimed |
| US-20250115578-A1 | AROMATIC FUSED RING NAV1.8 INHIBITOR, AND USE THEREOF | CHENGDU KANGHONG PHARMACEUTICAL CO., LTD. (CN) | 2025-04-10 | — | — | US | disclosed |
| EP-4455130-A1 | AROMATIC FUSED RING NAV1.8 INHIBITOR, AND USE THEREOF | Chengdu Kanghong Pharmaceutical Co., Ltd. (CN) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023138599-A1 | AROMATIC FUSED RING NAV1.8 INHIBITOR, AND USE THEREOF | 成都康弘药业集团股份有限公司 | 2023-07-27 | — | — | WO | disclosed |
| CN-116462662-A | Aromatic ring Nav1.8 inhibitor and application thereof | 成都康弘药业集团股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-108430986-B | Fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2021-08-31 | — | — | CN | disclosed |
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-04 | — | — | US | disclosed |
| US-20180305353-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-10-25 | — | — | US | disclosed |
| EP-3368521-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-09-05 | — | — | EP | disclosed |
| CN-108430986-A | fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2018-08-21 | — | — | CN | disclosed |
| WO-2017072039-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |
| CN-104592197-A | Preparation method of besifloxacin hydrochloride | GUANGXI RENHENG PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO LTD | 2015-05-06 | — | — | CN | disclosed |
| CN-1751025-B | Diamine derivatives | DAIICHI SEIYAKU CO | 2010-05-12 | — | — | CN | disclosed |
| EP-0538100-B1 | Process for the preparation of fluoro-quinolin-3-carboxylic acid derivatives | AVENTIS PHARMA SA (FR) | 2002-02-06 | — | — | EP | disclosed |
| CN-1027369-C | Excitatory amino acid antagonists | MERRELL DOW PHARMA (US) | 1995-01-11 | — | — | CN | disclosed |
| CN-1047292-A | EAA antagonists | MERRELL DOW PHARMA (US) | 1990-11-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305353-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, BCHE, ACHE | ALDH1A1 468/4885MAPT 2284/4885SMN1; SMN2 3061/4885 |
| US-20250115578-A1 | AROMATIC FUSED RING NAV1.8 INHIBITOR, AND USE THEREOF | SCN8A, SCN10A, SCN7A | ALDH1A1 3194/4885MAPT 1605/4885SMN1; SMN2 794/4885 |
| US-10550116-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, BCHE, ACHE | ALDH1A1 468/4885MAPT 2284/4885SMN1; SMN2 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.