Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | STK10 | O94804 | 1/20 | 0.37 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1262778 | 0.84 | HSD11B1 (0.59) | HSD11B1TRPA1TRPM8TRPV1AR | |
| SCHEMBL29010101 | 0.81 | HSD11B1 (0.43) | HSD11B1TRPA1TRPM8TRPV1P2RX7 | |
| SCHEMBL1041749 | 0.81 | NOTUM (0.43) | HSD11B1ARP2RX7NOTUMALDH1A1 | |
| SCHEMBL3992465 | 0.79 | HSD11B1 (0.47) | HSD11B1TRPA1TRPM8TRPV1AR | |
| SCHEMBL27907878 | 0.78 | CYP2A6 (0.56) | HSD11B1ARNOTUMPDK2ALDH1A1 | |
| SCHEMBL197671 | 0.78 | HSD11B1 (0.56) | HSD11B1TRPA1TRPM8TRPV1AR | |
| SCHEMBL23044990 | 0.78 | HSD11B1 (0.43) | HSD11B1TRPA1TRPM8TRPV1AR | |
| SCHEMBL11967616 | 0.77 | HSD11B1 (0.49) | HSD11B1TRPA1ARNOTUMPDK2 | |
| SCHEMBL6067687 | 0.77 | HSD11B1 (0.55) | HSD11B1ARP2RX7NOTUMPDK2 | |
| SCHEMBL8722602 | 0.76 | NOTUM (0.50) | NOTUMPDK2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1955990-B1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVES | TORAY FINECHEMICALS CO LTD (JP) | 2012-08-22 | — | — | EP | disclosed |
| US-20100036167-A1 | PROCESS FOR PRODUCTION OF 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | TORAY FINE CHEMICALS CO., LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-2100874-A1 | PROCESS FOR PRODUCTION OF 2,2'-BIS(TRIFLUOROMETHYL)- 4,4'-DIAMINOBIPHENYL | Toray Fine Chemicals Co., Ltd. (JP) | 2009-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036167-A1 | PROCESS FOR PRODUCTION OF 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | DDT, DBF4, CYP4B1 | HSD11B1 2225/4885TRPA1 1315/4885TRPM8 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.