Haliclonadiamine

Haliclonadiamine

SCHEMBL3199723

C1=C/[C@H]2[C@@H]3CCCC[C@H]3C[C@H]2NCCCN[C@@H]2C[C@@H]3CCCC[C@H]3[C@@H]2/C=C/1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPAS1 Q99814 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Haliclonadiamine SCHEMBL6264467 1.00 EPAS1 (1.00) EPAS1
SCHEMBL6899307 0.72 EPAS1 (0.56) EPAS1
SCHEMBL4623146 0.72 EPAS1 (0.56) EPAS1
SCHEMBL16878076 0.68
SCHEMBL16878031 0.66
SCHEMBL19541639 0.66 EPAS1 (0.48) EPAS1
SCHEMBL23946276 0.65
SCHEMBL4904117 0.65
SCHEMBL14828404 0.65
SCHEMBL9486149 0.65 EPAS1 (0.47) EPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1776071-A2 COATED VAGINAL DEVICES FOR VAGINAL DELIVERY OF THERAPEUTICALLY EFFECTIVE AND/ OR HEALTH-PROMOTING AGENTS UMD, Inc. (US) 2007-04-25 EP claimed
WO-2006017341-A2 COATED VAGINAL DEVICES FOR VAGINAL DELIVERY OF THERAPEUTICALLY EFFECTIVE AND/ OR HEALTH-PROMOTING AGENTS UMD, INC. (US) 2006-02-16 WO claimed
US-20050276836-A1 Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents UMD, INC. 2005-12-15 US claimed
WO-2005084157-A2 METHODS OF TREATING DISEASE THROUGH THE ADMINISTRATION OF A MANZAMINE ANALOG OR DERIVATIVE UNIVERSITY OF MISSISSIPPI (US) 2005-09-15 WO claimed
US-20050085554-A1 Methods of treating disease through the administration of a manzamine analog or derivative MISSISSIPPI, UNIVERSITY OF, THE 2005-04-21 US claimed
US-20100028469-A1 Extracts of Cranberry and Methods of Using Thereof HERBALSCIENCE GROUP, LLC (US) 2010-02-04 US disclosed
US-20080154035-A1 COUPLING METHOD BETWEEN INTRAMOLECULAR CARBON IN UNSATURATED HYDROCARBON COMPOUND USING ORGANO-INDIUM COMPOUND AS COUPLING AGENT PHIL HO LEE (KR) 2008-06-26 US disclosed
EP-1776071-A2 COATED VAGINAL DEVICES FOR VAGINAL DELIVERY OF THERAPEUTICALLY EFFECTIVE AND/ OR HEALTH-PROMOTING AGENTS UMD, Inc. (US) 2007-04-25 EP disclosed
WO-2006017341-A2 COATED VAGINAL DEVICES FOR VAGINAL DELIVERY OF THERAPEUTICALLY EFFECTIVE AND/ OR HEALTH-PROMOTING AGENTS UMD, INC. (US) 2006-02-16 WO disclosed
US-20050276836-A1 Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents UMD, INC. 2005-12-15 US disclosed
WO-2005084157-A2 METHODS OF TREATING DISEASE THROUGH THE ADMINISTRATION OF A MANZAMINE ANALOG OR DERIVATIVE UNIVERSITY OF MISSISSIPPI (US) 2005-09-15 WO disclosed
US-20050085554-A1 Methods of treating disease through the administration of a manzamine analog or derivative MISSISSIPPI, UNIVERSITY OF, THE 2005-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085554-A1 Methods of treating disease through the administration of a manzamine analog or derivative MANBA, MAN2A1, MAN2B1 EPAS1 4545/4885
US-20080154035-A1 COUPLING METHOD BETWEEN INTRAMOLECULAR CARBON IN UNSATURATED HYDROCARBON COMPOUND USING ORGANO-INDIUM COMPOUND AS COUPLING AGENT AHR, INTS9, ARNT EPAS1 3560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.