SCHEMBL4623146

SCHEMBL4623146

C1=CC2CC3CCCCC3C2C=C1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPAS1 Q99814 1/20 0.56
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6899307 0.78 EPAS1 (0.56) EPAS1
SCHEMBL8155771 0.76 EPAS1 (0.36) EPAS1ALDH1A1
SCHEMBL6263752 0.73 EPAS1 (0.37) EPAS1
Haliclonadiamine SCHEMBL6264467 0.72 EPAS1 (1.00) EPAS1
Haliclonadiamine SCHEMBL3199723 0.72 EPAS1 (1.00) EPAS1
SCHEMBL10318483 0.72 ALDH1A1 (0.42) EPAS1ALDH1A1
SCHEMBL6911299 0.69 EPAS1 (0.33) EPAS1
SCHEMBL1653614 0.68 ALDH1A1 (0.33) EPAS1ALDH1A1
SCHEMBL8008351 0.68 EPAS1 (0.35) EPAS1
SCHEMBL7530985 0.68 EPAS1 (0.32) EPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006134-B1 NORBORNENE POLYMER AND PROCESS FOR THE PREPARATION THEREOF NIPPON ZEON CO (JP) 2003-10-15 EP claimed
US-6525144-B1 Heat resistant, nondeforming molding materials NIPPON ZEON CO., LTD. (JP) 2003-02-25 US claimed
EP-1006134-A1 NORBORNENE POLYMER AND PROCESS FOR THE PREPARATION THEREOF NIPPON ZEON CO., LTD. (JP) 2000-06-07 EP claimed
EP-0994885-A1 NEW METALLOCENE COMPOUNDS FOR THE POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS BOREALIS A/S (DK) 2000-04-26 EP claimed
WO-1999002540-A1 NEW METALLOCENE COMPOUNDS FOR THE POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS BOREALIS A/S (DK) 1999-01-21 WO claimed
CN-113402641-B Metallocene catalyst, preparation method and application 北京化工大学 2022-09-20 CN disclosed
CN-113943315-A Indenyl-containing rare earth metal complex, preparation method and application thereof 上海大学 2022-01-18 CN disclosed
CN-113402641-A Metallocene catalyst, preparation method and application 北京化工大学 2021-09-17 CN disclosed
WO-2021176213-A1 PROCESS FOR THE PREPARATION OF CYCLOPENTADIENIDE-BASED ANSA LIGANDS CAMBRIDGE ENTERPRISE LIMITED (GB) 2021-09-10 WO disclosed
US-9919300-B2 1-hexene production process SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-20 US disclosed
EP-2484685-B1 TRANSITION METAL COMPLEX, PREPARATION METHOD FOR SAID TRANSITION METAL COMPLEX, TRIMERIZATION CATALYST, PREPARATION METHOD FOR 1-HEXENE, PREPARATION METHOD FOR ETHYLENE POLYMER, SUBSTITUTED CYCLOPENTADIENE COMPOUND, AND PREPARATION METHOD FOR SAID SUBSTITUTED CYCLOPENTADIENE COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-11-01 EP disclosed
US-20170036200-A1 1-HEXENE PRODUCTION PROCESS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-09 US disclosed
WO-1999002540-A1 NEW METALLOCENE COMPOUNDS FOR THE POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS BOREALIS A/S (DK) 1999-01-21 WO disclosed
WO-1998037106-A1 POLYMERIZATION CATALYST SYSTEMS COMPRISING HETEROCYCLIC FUSED CYCLOPENTADIENIDE LIGANDS EXXON CHEMICAL PATENTS INC. (US) 1998-08-27 WO disclosed
EP-0563365-B1 PREPARATION OF METAL COORDINATION COMPLEX DOW CHEMICAL CO (US) 1997-11-05 EP disclosed
EP-0619827-B1 ETHYLENE INTERPOLYMER POLYMERIZATIONS DOW CHEMICAL CO (US) 1996-06-12 EP disclosed
EP-0702687-A1 METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Montell Technology Company bv (NL) 1996-03-27 EP disclosed
WO-1995027717-A1 METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS MONTELL TECHNOLOGY COMPANY BV (NL) 1995-10-19 WO disclosed
EP-0563365-A1 PREPARATION OF METAL COORDINATION COMPLEX THE DOW CHEMICAL COMPANY (US) 1993-10-06 EP disclosed
WO-1993008199-A1 PREPARATION OF METAL COORDINATION COMPLEX THE DOW CHEMICAL COMPANY (US) 1993-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170036200-A1 1-HEXENE PRODUCTION PROCESS AP1M1, HK1, CYC1 EPAS1 2885/4885ALDH1A1 1321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.