Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.53 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3205711 | 0.94 | LTA4H (0.60) | LMNAL3MBTL1KDM4ELTA4HS1PR1 | |
| SCHEMBL3206438 | 0.88 | KMT2A (0.60) | LMNAL3MBTL1KDM4ELTA4HS1PR1 | |
| SCHEMBL3199117 | 0.87 | LMNA (0.73) | LMNAL3MBTL1LTA4HS1PR1S1PR3 | |
| Trifluoroacetic Acid SCHEMBL948584 | 0.87 | LTA4H (0.56) | LMNAL3MBTL1KDM4ELTA4HS1PR1 | |
| Trifluoroacetic Acid SCHEMBL948191 | 0.85 | S1PR1 (0.56) | LMNAL3MBTL1KDM4ELTA4HS1PR1 | |
| Trifluoroacetic Acid SCHEMBL946574 | 0.84 | S1PR1 (0.58) | LMNAL3MBTL1KDM4ELTA4HS1PR1 | |
| Trifluoroacetic Acid SCHEMBL947984 | 0.84 | S1PR1 (0.58) | LMNAL3MBTL1KDM4ELTA4HS1PR1 | |
| Trifluoroacetic Acid SCHEMBL948072 | 0.84 | S1PR1 (0.58) | LMNAL3MBTL1KDM4ELTA4HS1PR1 | |
| SCHEMBL3208902 | 0.83 | KDM4E (0.54) | LMNAL3MBTL1KDM4ELTA4HS1PR1 | |
| SCHEMBL15890981 | 0.83 | S1PR1 (0.71) | LTA4HS1PR1S1PR3S1PR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937090-B2 | Parakeratosis inhibitor, pore-shrinking agent and external composition for skin | SHISEIDO COMPANY, LTD. (JP) | 2015-01-20 | — | — | US | disclosed |
| US-20120232111-A1 | Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin | SHISEIDO COMPANY, LTD. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-1941861-A1 | WRINKLE-IMPROVING AGENT | Shiseido Company, Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
| EP-1880711-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | LMNA 133/4885L3MBTL1 874/4885KDM4E 4157/4885 |
| US-20120232111-A1 | Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin | CUTA, AAAS, NUP160 | LMNA 277/4885L3MBTL1 1100/4885KDM4E 3885/4885 |
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | LMNA 105/4885L3MBTL1 999/4885KDM4E 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.