Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29008206 | 0.97 | ALDH1A1 (0.58) | ALDH1A1TSHRPBRM1POLBFEN1 | |
| SCHEMBL17329160 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TSHRPBRM1POLBFEN1 | |
| SCHEMBL145510 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TSHRPBRM1POLBFEN1 | |
| SCHEMBL1135187 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TSHRPBRM1PARP1HPGD | |
| SCHEMBL793494 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRPBRM1POLBFEN1 | |
| SCHEMBL15540940 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRPBRM1POLBFEN1 | |
| SCHEMBL2867748 | 0.84 | PBRM1 (0.58) | ALDH1A1PBRM1KMT2AMEN1LMNA | |
| SCHEMBL1397518 | 0.84 | TSHR (0.51) | ALDH1A1TSHRPBRM1POLBFEN1 | |
| SCHEMBL1805872 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRPBRM1POLBFEN1 | |
| Hydrochloric Acid SCHEMBL4372223 | 0.83 | TSHR (0.50) | ALDH1A1TSHRPBRM1POLBFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 684 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118754844-A | Preparation method of diclofenac sodium intermediate | 世华合创生物技术开发(山东)有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-115047107-B | Method for detecting residues of fluopicolide, cyazofamid and metabolites thereof on ginseng | 山东省农业科学院 | 2024-03-19 | — | — | CN | claimed |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | claimed |
| CN-117110458-A | Method for detecting halogenated benzamide by solid phase extraction-liquid chromatography tandem mass spectrometry | 浙江工业大学 | 2023-11-24 | — | — | CN | claimed |
| US-11708322-B2 | Process for preparation of 2,6-dichlorobenzonitrile | ARYSTA LIFESCIENCE INC. (US) | 2023-07-25 | — | — | US | claimed |
| EP-4204400-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | Fibrogen, Inc. (US) | 2023-07-05 | — | — | EP | claimed |
| CN-116348450-A | Compounds, compositions and methods for histone lysine demethylase inhibition | 菲布罗根有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-113038835-B | Preparation method of 2, 6-dichlorobenzonitrile | 爱利思达生命科学有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-115047107-A | Method for detecting residues of fluopicolide, cyazofamid and metabolites thereof on ginseng | 山东省农业科学院 | 2022-09-13 | — | — | CN | claimed |
| CN-112305131-B | GC-Orbitrap-MS screening and analyzing method for pesticide residues in animal derived food | 中国农业科学院农业质量标准与检测技术研究所 | 2021-09-21 | — | — | CN | claimed |
| EP-1204866-A2 | IMMUNOASSAY FOR PESTICIDES AND THEIR DEGRADATION PRODUCTS | Exiqon A/S (DK) | 2002-05-15 | — | — | EP | claimed |
| US-6262040-B1 | Indazole derivatives and their use as inhibitors of phosphodiesterase (PDE) type IV and the production of tumor necrosis factor (TNF) | PFIZER INC | 2001-07-17 | — | — | US | claimed |
| WO-2001007912-A2 | IMMUNOASSAY FOR PESTICIDES AND THEIR DEGRADATION PRODUCTS | EXIQON A/S (US) | 2001-02-01 | — | — | WO | claimed |
| US-6180637-B1 | THERAPY FOR PARKINSON, ALZHEIMER DISEASE | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2001-01-30 | — | — | US | claimed |
| EP-0931075-A1 | INDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF PHOSPHODIESTERASE (PDE) TYPE IV AND THE PRODUCTION OF TUMOR NECROSIS FACTOR (TNF) | PFIZER INC. (US) | 1999-07-28 | — | — | EP | claimed |
| WO-1998009961-A1 | INDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF PHOSPHODIESTERASE (PDE) TYPE IV AND THE PRODUCTION OF TUMOR NECROSIS FACTOR (TNF) | PFIZER INC. (US) | 1998-03-12 | — | — | WO | claimed |
| CN-1087920-A | The enzymatic of phenol and aromatic amine high molecular polymer is synthetic | UNIV JILIN (CN) | 1994-06-15 | — | — | CN | claimed |
| WO-1993014062-A1 | ANTHELMINTIC β-KETOAMIDES | THE UPJOHN COMPANY (US) | 1993-07-22 | — | — | WO | claimed |
| US-5096710-A | Cockroaches, juvenile hormone or chitin synthesis inhibitor, dextrin, plant oil | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-17 | — | — | US | claimed |
| US-4942232-A | FOR PRINTING AND DYEING CELLULOSE FIBERS | BASF AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708322-B2 | Process for preparation of 2,6-dichlorobenzonitrile | DDT, DCUN1D2, DCUN1D4 | ALDH1A1 1703/4885TSHR 3640/4885PBRM1 669/4885 |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | KDM5C, KDM5B, KDM5A | ALDH1A1 2449/4885TSHR 4662/4885PBRM1 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.