Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | JAK1 | P23458 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320037 | 0.86 | ALDH1A1 (0.61) | ALDH1A1JAK1TSHRPBRM1POLB | |
| SCHEMBL29008206 | 0.84 | ALDH1A1 (0.58) | ALDH1A1JAK1TSHRPBRM1POLB | |
| SCHEMBL1613338 | 0.84 | MMP2 (0.43) | ALDH1A1JAK1TSHRPOLBPARP1 | |
| SCHEMBL147437 | 0.83 | ALDH1A1 (0.52) | ALDH1A1JAK1TSHRNR4A2P2RX7 | |
| SCHEMBL19972032 | 0.83 | ALDH1A1 (0.71) | ALDH1A1JAK1TSHRNR4A2P2RX7 | |
| SCHEMBL1188823 | 0.81 | ALDH1A1 (0.50) | ALDH1A1JAK1TSHRNR4A2P2RX7 | |
| Hydrochloric Acid SCHEMBL8993445 | 0.81 | ALDH1A1 (0.50) | ALDH1A1JAK1TSHRNR4A2P2RX7 | |
| SCHEMBL24743503 | 0.78 | TSHR (0.46) | ALDH1A1JAK1TSHRNR4A2P2RX7 | |
| SCHEMBL1135187 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRPBRM1PARP1NPC1 | |
| SCHEMBL17329160 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRPBRM1POLBFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408454-B1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP (CA) | 2024-07-24 | — | — | EP | disclosed |
| US-20240190828-A1 | Small Molecule Inhibitors of PBRM1-BD2 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-06-13 | — | — | US | disclosed |
| CN-117964560-A | Method for constructing quinazolinone derivative through oxidization | 淮阴工学院 | 2024-05-03 | — | — | CN | disclosed |
| CN-117736192-A | PI3K/HDAC dual inhibitor and application thereof | 安徽中医药大学 | 2024-03-22 | — | — | CN | disclosed |
| EP-4291195-A1 | SMALL MOLECULE INHIBITORS OF PBRM1-BD2 | The Medical College of Wisconsin, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-107252429-B | Novel anti-inflammatory agent | 雷斯韦洛吉克斯公司 | 2023-06-16 | — | — | CN | disclosed |
| WO-2022174085-A1 | SMALL MOLECULE INHIBITORS OF PBRM1-BD2 | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2022-08-18 | — | — | WO | disclosed |
| WO-2022174085-A1 | SMALL MOLECULE INHIBITORS OF PBRM1-BD2 | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2022-08-18 | — | — | WO | disclosed |
| US-11407719-B2 | Anti-inflammatory agents | RESVERLOGIX CORP. (CA) | 2022-08-09 | — | — | US | disclosed |
| US-20210070716-A1 | ANTI-INFLAMMATORY AGENTS | HEPALINK (HONG KONG) LIMITED (HK) | 2021-03-11 | — | — | US | disclosed |
| US-4307113-A | TREATMENT OF DIABETES | SANDOZ, INC. (US) | 1981-12-22 | — | — | US | disclosed |
| US-4191840-A | Oxamic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-03-04 | — | — | US | disclosed |
| US-4160100-A | OXAMIC ACID DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-07-03 | — | — | US | disclosed |
| US-4154961-A | Oxamic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4069343-A | OXAMIC ACID DERIVATIVES FOR THE PREVENTION OF IMMEDIATE TYPE HYPERSENSITIVITY REACTIONS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-01-17 | — | — | US | disclosed |
| US-4054666-A | Compositions and methods of treating immediate hypersensitivity reactions with thiazolyl oxamic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054661-A | Pyridyl oxamic acid derivatives and use in the prevention of allergic reactions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054657-A | Pyrimidinyl oxamic acids and esters, and compositions and methods for the suppression of allergic manifestations | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-4036837-A | 2 Alkoxyoxamoyl-pyrazines | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
| US-3966965-A | Oxamic acid derivatives for the prevention of immediate type hypersensitivity reactions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407719-B2 | Anti-inflammatory agents | VCAM1, ICAM1, IL6 | ALDH1A1 587/4885JAK1 706/4885TSHR 4418/4885 |
| US-20210070716-A1 | ANTI-INFLAMMATORY AGENTS | VCAM1, ICAM1, IL6 | ALDH1A1 587/4885JAK1 706/4885TSHR 4418/4885 |
| US-20240190828-A1 | Small Molecule Inhibitors of PBRM1-BD2 | BRD2, PBRM1, BRDT | ALDH1A1 4514/4885JAK1 3220/4885TSHR 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.