Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003830 | 0.84 | PARP1 (0.46) | ALDH1A1CXCR1CXCR2TSHRHPGD | |
| SCHEMBL320037 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRNPC1GLAHPGD | |
| SCHEMBL29008206 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRNPC1GLAHPGD | |
| SCHEMBL2844436 | 0.81 | ALDH1A1 (0.71) | ALDH1A1CXCR1CXCR2TSHRNPC1 | |
| SCHEMBL696250 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRNPC1GLAHPGD | |
| SCHEMBL8262560 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRNPC1GLAHPGD | |
| SCHEMBL11847260 | 0.79 | L3MBTL1 (0.44) | ALDH1A1CXCR1CXCR2NPC1GLA | |
| Hydrochloric Acid SCHEMBL7952153 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRNPC1GLAHPGD | |
| SCHEMBL18938848 | 0.78 | POLB (0.40) | ALDH1A1CXCR1CXCR2TSHRNPC1 | |
| SCHEMBL22904424 | 0.77 | CA1 (0.48) | ALDH1A1CXCR1CXCR2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003294-A | New synthesis method of medical intermediate 2-bromo-6-chlorobenzonitrile | 常州大学 | 2023-04-25 | — | — | CN | claimed |
| CN-116003294-A | New synthesis method of medical intermediate 2-bromo-6-chlorobenzonitrile | 常州大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-116003294-A | New synthesis method of medical intermediate 2-bromo-6-chlorobenzonitrile | 常州大学 | 2023-04-25 | — | — | CN | disclosed |
| US-20140171408-A1 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2014-06-19 | — | — | US | disclosed |
| US-8697708-B2 | Azabenzothiazole compounds, compositions and methods of use | F. HOFFMANN-LA ROCHE AG (CH) | 2014-04-15 | — | — | US | disclosed |
| EP-2616072-A1 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F.HOFFMANN-LA ROCHE AG (CH) | 2013-07-24 | — | — | EP | disclosed |
| CN-103209695-A | Azabenzothiazole compounds, compositions and methods of use | HOFFMANN LA ROCHE | 2013-07-17 | — | — | CN | disclosed |
| US-20120202788-A1 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2012-08-09 | — | — | US | disclosed |
| WO-2012035039-A1 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2012-03-22 | — | — | WO | disclosed |
| EP-0594179-B1 | N-alkoxymethyl benzamide derivative and manufacturing method therefor, and manufacturing method for benzamide derivative using this N-alkoxymethyl benzamide derivate | YASHIMA KAGAKU KOGYO KK (JP) | 1996-09-25 | — | — | EP | disclosed |
| US-5354905-A | N-alkoxymethyl benzamide derivative and manufacturing method therefor, and manufacturing method for benzamide derivative using this N-alkoxymethyl benzamide derivative | YASHIMA CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0594179-A1 | N-alkoxymethyl benzamide derivative and manufacturing method therefor, and manufacturing method for benzamide derivative using this N-alkoxymethyl benzamide derivate | YASHIMA CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171408-A1 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F12, CHRM1, NPY1R | ALDH1A1 1372/4885CXCR1 366/4885CXCR2 537/4885 |
| US-20120202788-A1 | AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F12, CHRM1, NPY1R | ALDH1A1 1372/4885CXCR1 366/4885CXCR2 537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.