SCHEMBL3200978

SCHEMBL3200978

Cc1ccc(S(OS(=O)(=O)c2ccc(F)cc2F)(c2ccccc2)c2ccccc2)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
MAPT P10636 3/20 0.42
KDM4E B2RXH2 3/20 0.42
F2 P00734 2/20 0.42
HPGD P15428 2/20 0.39
POLB P06746 1/20 0.39
ALOX12 P18054 1/20 0.39
GFER P55789 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
GAA P10253 2/20 0.37
PKM P14618 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HSD11B1 P28845 1/20 0.35
MMP14 P50281 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
HTR2A P28223 2/20 0.34
HTR2C P28335 2/20 0.34
XBP1 P17861 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2954165 0.88 HTR2A (0.39) ALDH1A1MAPTKDM4EF2TSHR
SCHEMBL548240 0.88 FFAR4 (0.38) ALDH1A1MAPTKDM4EF2TSHR
SCHEMBL3206009 0.87 ALDH1A1 (0.44) ALDH1A1MAPTKDM4EF2HPGD
SCHEMBL2537987 0.85 HTR2A (0.41) ALDH1A1GAAPKMHTR2AHTR2C
SCHEMBL3204764 0.85 HTR2A (0.36) ALDH1A1KDM4EHPGDTSHRMAPK1
SCHEMBL3189928 0.84 TSHR (0.37) ALDH1A1TSHRMAPK1GAAHTR2A
SCHEMBL3193930 0.84 ALDH1A1 (0.40) ALDH1A1MAPTKDM4EF2HPGD
SCHEMBL2964612 0.83 BCHE (0.40) ALDH1A1MAPTGAAFFAR4HTT
SCHEMBL3191502 0.82 ALDH1A1 (0.41) ALDH1A1MAPTKDM4EF2HPGD
SCHEMBL4861379 0.81 ALDH1A1 (0.48) ALDH1A1MAPTKDM4EF2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed