SCHEMBL3204764

SCHEMBL3204764

Cc1cc(C)cc(S(OS(=O)(=O)c2ccc(F)cc2F)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.36
HTR2C P28335 3/20 0.36
KCNH2 Q12809 3/20 0.36
ALDH1A1 P00352 2/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
KAT6A Q92794 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
ABCC9 O60706 1/20 0.34
ABCC8 Q09428 1/20 0.34
KCNJ11 Q14654 1/20 0.34
KCNJ8 Q15842 1/20 0.34
KDM4E B2RXH2 2/20 0.33
FFAR4 Q5NUL3 1/20 0.33
PTGDR Q13258 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
NAT1 P18440 1/20 0.33
HPGD P15428 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2954165 0.91 HTR2A (0.39) HTR2AHTR2CKCNH2ALDH1A1GAA
SCHEMBL2537987 0.90 HTR2A (0.41) HTR2AHTR2CKCNH2ALDH1A1GAA
SCHEMBL548240 0.87 FFAR4 (0.38) HTR2AHTR2CKCNH2ALDH1A1GAA
SCHEMBL2964612 0.85 BCHE (0.40) ALDH1A1GAAKAT6ASMN1; SMN2FFAR4
SCHEMBL3200978 0.85 ALDH1A1 (0.42) HTR2AHTR2CKCNH2ALDH1A1GAA
SCHEMBL3194937 0.83 FFAR4 (0.41) HTR2ATSHRMAPK1FFAR4
SCHEMBL3195800 0.83 HSD11B1 (0.42) HTR2AHTR2CKCNH2ALDH1A1GAA
SCHEMBL3189928 0.83 TSHR (0.37) HTR2AHTR2CKCNH2ALDH1A1GAA
SCHEMBL2956300 0.83 CNR1 (0.41) HTR2AHTR2CKCNH2ALDH1A1GAA
SCHEMBL3197589 0.83 ABCC9 (0.34) HTR2AHTR2CKCNH2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed