SCHEMBL4861379

SCHEMBL4861379

Cc1ccc(S(=O)(=O)OS(c2ccccc2)(c2ccccc2)c2ccc(C)cc2C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
MAPT P10636 3/20 0.48
KDM4E B2RXH2 2/20 0.48
F2 P00734 2/20 0.48
HPGD P15428 2/20 0.44
POLB P06746 1/20 0.44
ALOX12 P18054 1/20 0.44
GFER P55789 1/20 0.44
VDR P11473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HSD11B1 P28845 1/20 0.40
HTT P42858 2/20 0.40
FFAR4 Q5NUL3 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
RAPGEF4 Q8WZA2 1/20 0.39
KMT2A Q03164 2/20 0.39
XBP1 P17861 1/20 0.39
MMP14 P50281 1/20 0.39
GAA P10253 1/20 0.38
BCHE P06276 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3206009 0.92 ALDH1A1 (0.44) ALDH1A1MAPTKDM4EF2HPGD
SCHEMBL3201722 0.88 MCL1 (0.43) ALDH1A1MAPTKDM4EF2HPGD
SCHEMBL3127299 0.88 VDR (0.42) ALDH1A1MAPTKDM4EF2HPGD
SCHEMBL5408843 0.87 POLB (0.41) ALDH1A1MAPTKDM4EF2HPGD
SCHEMBL2955938 0.84 VDR (0.49) ALDH1A1KDM4EHPGDALOX12GFER
SCHEMBL3144536 0.84 VDR (0.49) ALDH1A1KDM4EHPGDALOX12GFER
SCHEMBL64190 0.84 VDR (0.49) ALDH1A1KDM4EHPGDALOX12GFER
SCHEMBL2964106 0.84 VDR (0.49) ALDH1A1KDM4EHPGDALOX12GFER
SCHEMBL2962485 0.84 VDR (0.49) ALDH1A1KDM4EHPGDALOX12GFER
SCHEMBL5408450 0.84 MCL1 (0.41) ALDH1A1MAPTKDM4EF2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323284-B2 Negative type radiation sensitive resin composition JSR CORPORATION (JP) 2008-01-29 US disclosed
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1113005-B1 Sulfonium salt compounds WAKO PURE CHEM IND LTD (JP) 2003-08-06 EP disclosed
US-20030022095-A1 Negative type radiation sensitive resin composition JSR CORPORATION (JP) 2003-01-30 US disclosed
EP-1238969-A2 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2002-09-11 EP disclosed
EP-1113005-A1 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2001-07-04 EP disclosed