SCHEMBL3201689

SCHEMBL3201689

Cc1cc(C)c(S(OS(=O)(=O)c2c(C(F)(F)F)cc(C(F)(F)F)cc2C(F)(F)F)(c2ccccc2)c2ccccc2)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C19 P33261 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP2D6 P10635 1/20 0.44
TSHR P16473 1/20 0.44
MAPT P10636 3/20 0.41
MAPK1 P28482 1/20 0.41
NR3C1 P04150 3/20 0.37
PGR P06401 3/20 0.37
NR3C2 P08235 3/20 0.37
FFAR4 Q5NUL3 1/20 0.37
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 3/20 0.34
LMNA P02545 2/20 0.34
HTT P42858 1/20 0.34
HSD11B1 P28845 1/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MCOLN3 Q8TDD5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3194661 0.91 HSD11B1 (0.35) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL3204881 0.90 CYP3A4 (0.38) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL5405543 0.88 MAPT (0.42) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL3183558 0.88 HSD11B1 (0.33) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL3199737 0.87 CYP3A4 (0.42) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL3201120 0.87 MCL1 (0.38) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL547991 0.86 MEN1 (0.48) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL547726 0.85 CYP1A2 (0.42) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL3199775 0.85 CYP1A2 (0.42) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL5415920 0.84 CYP3A4 (0.50) CYP1A2CYP3A4CYP2C19MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed