SCHEMBL3199775

SCHEMBL3199775

Cc1cc(C)c(S(OS(=O)(=O)c2c(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c2C(F)(F)F)(c2ccccc2)c2ccccc2)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C19 P33261 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
NR3C1 P04150 3/20 0.40
PGR P06401 3/20 0.40
NR3C2 P08235 3/20 0.40
FFAR4 Q5NUL3 2/20 0.40
MAPT P10636 2/20 0.39
MAPK1 P28482 1/20 0.39
RAPGEF4 Q8WZA2 4/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
METAP2 P50579 1/20 0.35
LMNA P02545 1/20 0.35
MCOLN3 Q8TDD5 1/20 0.35
APAF1 O14727 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3193036 0.89 HSD11B1 (0.33) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL3200054 0.88 FFAR4 (0.35) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL3203126 0.86 NR3C1 (0.32) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL3191940 0.86 ALDH1A1 (0.40) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL3201689 0.85 CYP1A2 (0.44) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL547726 0.84 CYP1A2 (0.42) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL5405543 0.84 MAPT (0.42) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL58786 0.84 FFAR4 (0.47) MEN1KMT2ANR3C1PGRNR3C2
SCHEMBL3140005 0.83 FFAR4 (0.42) CYP1A2CYP3A4CYP2C19MEN1KMT2A
SCHEMBL5415920 0.83 CYP3A4 (0.50) CYP1A2CYP3A4CYP2C19MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed