Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3202334 | 0.92 | MCL1 (0.37) | CYP3A4CYP2C19CYP1A2CYP2D6MAPT | |
| SCHEMBL3189170 | 0.90 | HSD11B1 (0.37) | CYP3A4CYP2C19CYP1A2CYP2D6MEN1 | |
| SCHEMBL3202138 | 0.89 | POLQ (0.34) | CYP3A4CYP2C19CYP1A2CYP2D6MEN1 | |
| SCHEMBL3203596 | 0.89 | MCL1 (0.43) | CYP3A4CYP2C19CYP1A2CYP2D6MEN1 | |
| SCHEMBL547991 | 0.88 | MEN1 (0.48) | CYP3A4CYP2C19CYP1A2CYP2D6MEN1 | |
| SCHEMBL3201689 | 0.87 | CYP1A2 (0.44) | CYP3A4CYP2C19CYP1A2CYP2D6MEN1 | |
| SCHEMBL547726 | 0.84 | CYP1A2 (0.42) | CYP3A4CYP2C19CYP1A2CYP2D6MEN1 | |
| SCHEMBL5415920 | 0.83 | CYP3A4 (0.50) | CYP3A4CYP2C19CYP1A2CYP2D6MEN1 | |
| SCHEMBL3191640 | 0.82 | CYP3A4 (0.35) | CYP3A4CYP2C19CYP2D6KMT2ATSHR | |
| SCHEMBL5405543 | 0.82 | MAPT (0.42) | CYP3A4CYP2C19CYP1A2CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8206888-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20100028800-A1 | RADIATION-SENSITIVE RESIN COMPOSITION | JSR CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-1953593-A1 | RADIATION-SENSITIVE RESIN COMPOSITION | JSR Corporation (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-7060414-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2006-06-13 | — | — | US | disclosed |
| US-20050158657-A1 | Radiation-sensitive resin composition | SUZUKI AKI (JP) | 2005-07-21 | — | — | US | disclosed |
| US-6899989-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2005-05-31 | — | — | US | disclosed |