SCHEMBL3201759

SCHEMBL3201759

CCCCNC(C)(C)c1ccccc1C1c2ccccc2-c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.50
BCHE P06276 1/20 0.50
HTR2A P28223 1/20 0.36
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
MAPT P10636 1/20 0.33
APAF1 O14727 1/20 0.33
KCNA5 P22460 1/20 0.32
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CHRM1 P11229 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3201597 0.80 BCHE (0.35) ACHEBCHEKMT2AALDH1A1KDM4E
SCHEMBL3216622 0.77 BCHE (0.33) ACHEBCHEALDH1A1KDM4EHPGD
SCHEMBL3213267 0.75 BCHE (0.36) ACHEBCHEHTR2AKMT2AMEN1
SCHEMBL3205293 0.74 GPR3 (0.34) ACHEBCHEHTR2AKMT2AMEN1
SCHEMBL3213298 0.72 NPSR1 (0.35) ACHEBCHEHTR2AKMT2AMEN1
SCHEMBL3211829 0.71 BCHE (0.35) ACHEBCHEALDH1A1APAF1
SCHEMBL3214577 0.70 BCHE (0.35) ACHEBCHE
SCHEMBL3204863 0.70 BCHE (0.34) ACHEBCHEALDH1A1APAF1
SCHEMBL3202576 0.70 BCHE (0.53) ACHEBCHEKDM4ETSHRCHRM2
SCHEMBL3677989 0.70 PNMT (0.39) ACHEBCHEALDH1A1HTR2BAPAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed