Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3206219 | 0.97 | L3MBTL1 (0.34) | L3MBTL1HDAC6 | |
| SCHEMBL3202717 | 0.93 | RXRA (0.36) | RXRAHDAC6RXRBRXRG | |
| SCHEMBL3122650 | 0.92 | SLC7A5 (0.32) | RXRAHDAC6RXRBRXRG | |
| SCHEMBL3206120 | 0.89 | RXRA (0.39) | L3MBTL1RXRARXRBRXRG | |
| SCHEMBL3126060 | 0.89 | HDAC6 (0.37) | RXRAHDAC6RXRBRXRG | |
| SCHEMBL3214864 | 0.85 | PDE4D (0.33) | L3MBTL1 | |
| SCHEMBL3215114 | 0.85 | HDAC6 (0.36) | L3MBTL1HDAC6 | |
| SCHEMBL3129127 | 0.85 | POLB (0.36) | L3MBTL1HDAC6 | |
| SCHEMBL3123577 | 0.84 | CTSL (0.35) | HDAC6 | |
| SCHEMBL3203001 | 0.84 | POLB (0.35) | L3MBTL1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029689-A1 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029689-A1 | PHOSPHODIESTERASE 4 INHIBITORS | PDE4A, PDE4B, PDE3B | L3MBTL1 3388/4885RXRA 2856/4885HDAC6 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.