Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243535 | 0.82 | MAPT (0.44) | KMT2AMAPTMEN1BACE1LMNA | |
| Hydrochloric Acid SCHEMBL8038931 | 0.79 | MAPT (0.43) | KMT2AMAPTMEN1BACE1LMNA | |
| SCHEMBL10105249 | 0.79 | ALDH1A1 (0.39) | KMT2AMAPTMEN1BACE1LMNA | |
| SCHEMBL4408209 | 0.79 | ALDH1A1 (0.39) | KMT2AMAPTMEN1BACE1LMNA | |
| SCHEMBL9022771 | 0.78 | ALDH1A1 (0.53) | KMT2AMAPTMEN1BACE1LMNA | |
| SCHEMBL11682442 | 0.76 | ALDH1A1 (0.50) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL1234089 | 0.76 | KMT2A (0.57) | KMT2AMAPTMEN1BACE1LMNA | |
| SCHEMBL2006984 | 0.75 | KMT2A (0.41) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL10134048 | 0.75 | ALDH1A1 (0.42) | KMT2AMAPTMEN1BACE1LMNA | |
| SCHEMBL9490421 | 0.75 | ALDH1A1 (0.43) | KMT2AMAPTMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | KRT18, H1-10, COL1A1 | KMT2A 1767/4885MAPT 446/4885MEN1 3588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.