Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10153024 | 0.89 | MAPT (0.45) | ALDH1A1TDP1KDM4ETSHRKMT2A | |
| SCHEMBL6243535 | 0.82 | MAPT (0.44) | ALDH1A1TDP1ADRA2ATSHRBACE1 | |
| Hydrochloric Acid SCHEMBL8038931 | 0.79 | MAPT (0.43) | ALDH1A1TDP1KDM4ETSHRBACE1 | |
| SCHEMBL10105249 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TDP1KDM4EADRA2ATSHR | |
| SCHEMBL3202085 | 0.79 | KMT2A (0.39) | ALDH1A1TDP1KDM4EADRA2ATSHR | |
| SCHEMBL9022771 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TDP1KDM4ETSHRBACE1 | |
| SCHEMBL11682442 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRKMT2AMAPT | |
| SCHEMBL28087334 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1KDM4EADRA2ATSHR | |
| SCHEMBL33874 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1KDM4EADRA2ATSHR | |
| SCHEMBL8521178 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1KDM4EADRA2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433617-B1 | Cosmetic composition containing microcapsules | HENKEL AG & CO KGAA (DE) | 2019-05-15 | — | — | EP | claimed |
| EP-1900393-B1 | Hydrogen peroxide activation with diones and imidazoles | HENKEL AG & CO KGAA (DE) | 2018-02-28 | — | — | EP | claimed |
| EP-1862198-B1 | Brightening and/or dyeing agent with urea derivatives | HENKEL AG & CO KGAA (DE) | 2017-04-05 | — | — | EP | claimed |
| EP-2173314-B1 | VAPORIZER SOLUTION, AND DYEING METHOD | HENKEL AG & CO KGAA (DE) | 2014-07-23 | — | — | EP | claimed |
| EP-2012742-B1 | BLEACHING AND/OR COLOURING AGENTS CONTAINING PIPERIDONES | HENKEL AG & CO KGAA (DE) | 2014-03-19 | — | — | EP | claimed |
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | claimed |
| US-10835478-B2 | Lightening method using special siloxane compounds | HENKEL AG & CO. KGAA (DE) | 2020-11-17 | — | — | US | disclosed |
| US-10328016-B2 | Dye composition with special non-ionic linear silicone polymers | HENKEL AG & CO. KGAA (DE) | 2019-06-25 | — | — | US | disclosed |
| US-10117825-B2 | Oxidation coloring composition with protein-siloxane polymers | HENKEL AG & CO. KGAA (DE) | 2018-11-06 | — | — | US | disclosed |
| US-10092502-B2 | Oxidative hair lighteners with special aminated silicone polymers | HENKEL AG & CO. KGAA (DE) | 2018-10-09 | — | — | US | disclosed |
| US-10080716-B2 | Packaging unit having particular aminated silicone polymer | HENKEL AG & CO. KGAA (DE) | 2018-09-25 | — | — | US | disclosed |
| US-20180221269-A1 | LIGHTENING METHOD USING SPECIAL SILOXANE COMPOUNDS | HENKEL AG & CO. KGAA (DE) | 2018-08-09 | — | — | US | disclosed |
| US-10039707-B2 | Oxidation dyeing agent having specific non-ionic silicone polymers | HENKEL AG & CO. KGAA (DE) | 2018-08-07 | — | — | US | disclosed |
| US-20170100322-A1 | HAIR DYE WITH CATIONIC POLYMER | HENKEL AG & CO. KGAA (DE) | 2017-04-13 | — | — | US | disclosed |
| US-4838893-A | AND TETRAAMINOPYRIDINES ASDEVELOPER COMPONENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-06-13 | — | — | US | disclosed |
| US-4661115-A | Hair dyeing agents | RUETGERSWERKE AKTIENGESELLSCHAFT (DE) | 1987-04-28 | — | — | US | disclosed |
| US-4402699-A | 2,4-DICHLORO-3-ALKYLIDINE-AMINOPHENOLS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1983-09-06 | — | — | US | disclosed |
| US-4371370-A | Oxidation hair dyes comprising bis-(2,4-diaminophenoxy)-alkanols as coupling components | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1983-02-01 | — | — | US | disclosed |
| US-4322212-A | AS COUPLERS WITH CONVENTIONAL DEVELOPERS IN AQUEOUS SOLUTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1982-03-30 | — | — | US | disclosed |
| US-4226595-A | Oxidation hair-coloring preparation based upon N,N-bis-(β-hydroxyethyl)-m-phenylenediamines | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1980-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10080716-B2 | Packaging unit having particular aminated silicone polymer | KRT18, C9, AOC1 | ALDH1A1 69/4885TDP1 3275/4885KDM4E 500/4885 |
| US-20180221269-A1 | LIGHTENING METHOD USING SPECIAL SILOXANE COMPOUNDS | KRT18, KIT, DSC1 | ALDH1A1 951/4885TDP1 2973/4885KDM4E 67/4885 |
| US-10092502-B2 | Oxidative hair lighteners with special aminated silicone polymers | KRT18, ALDH7A1, MARK1 | ALDH1A1 64/4885TDP1 3619/4885KDM4E 319/4885 |
| US-10039707-B2 | Oxidation dyeing agent having specific non-ionic silicone polymers | KRT18, IK, MARK1 | ALDH1A1 639/4885TDP1 3361/4885KDM4E 128/4885 |
| US-10328016-B2 | Dye composition with special non-ionic linear silicone polymers | KRT18, MARK1, IK | ALDH1A1 1262/4885TDP1 3698/4885KDM4E 533/4885 |
| US-10835478-B2 | Lightening method using special siloxane compounds | KRT18, KIT, DSC1 | ALDH1A1 951/4885TDP1 2973/4885KDM4E 67/4885 |
| US-10117825-B2 | Oxidation coloring composition with protein-siloxane polymers | KRT18, CUTA, IK | ALDH1A1 487/4885TDP1 4086/4885KDM4E 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.