Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3126412 | 0.95 | TSHR (0.42) | HDAC6L3MBTL1ALDH1A1MAPK1KMT2A | |
| SCHEMBL3212923 | 0.95 | MAPK1 (0.39) | HDAC6L3MBTL1ALDH1A1MAPK1KMT2A | |
| SCHEMBL3203192 | 0.93 | RXRA (0.42) | HDAC6ALDH1A1MAPK1RXRARXRB | |
| SCHEMBL3120590 | 0.92 | LMNA (0.38) | HDAC6MAPK1KMT2ARAB9ANPSR1 | |
| SCHEMBL3131869 | 0.86 | TSHR (0.46) | L3MBTL1TSHRLMNARXRARXRB | |
| SCHEMBL3201995 | 0.85 | HRH4 (0.39) | HDAC6ALDH1A1MAPK1KMT2ANPC1 | |
| SCHEMBL3192199 | 0.85 | HRH4 (0.39) | HDAC6L3MBTL1ALDH1A1MAPK1KMT2A | |
| SCHEMBL3205217 | 0.85 | RXRA (0.40) | HDAC6RAB9ARXRALTC4S | |
| SCHEMBL3129630 | 0.85 | MAPT (0.44) | L3MBTL1ALDH1A1MAPK1KMT2ANPC1 | |
| SCHEMBL3120270 | 0.84 | PDE4A (0.38) | HDAC6KMT2ALMNARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029689-A1 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029689-A1 | PHOSPHODIESTERASE 4 INHIBITORS | PDE4A, PDE4B, PDE3B | HDAC6 329/4885L3MBTL1 3388/4885ALDH1A1 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.