Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 8/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3126412 | 0.96 | TSHR (0.42) | MAPK1L3MBTL1TSHRMAPTNPSR1 | |
| SCHEMBL3202677 | 0.95 | HDAC6 (0.36) | MAPK1L3MBTL1TSHRNPSR1LMNA | |
| SCHEMBL3120590 | 0.89 | LMNA (0.38) | MAPK1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3126242 | 0.88 | PDE4B (0.44) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3215234 | 0.88 | PDE4B (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3203192 | 0.88 | RXRA (0.42) | MAPK1MAPTHDAC6ALDH1A1 | |
| SCHEMBL3210241 | 0.88 | RXRA (0.39) | MAPK1L3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL3120710 | 0.87 | L3MBTL1 (0.51) | MAPK1L3MBTL1TP53TSHRPDE4A | |
| SCHEMBL3205217 | 0.86 | RXRA (0.40) | MAPTHDAC6SMN1; SMN2 | |
| SCHEMBL3129630 | 0.86 | MAPT (0.44) | MAPK1L3MBTL1TSHRPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029689-A1 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029689-A1 | PHOSPHODIESTERASE 4 INHIBITORS | PDE4A, PDE4B, PDE3B | MAPK1 1371/4885L3MBTL1 3388/4885TP53 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.