Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3202919 | 1.00 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1POLBL3MBTL1 | |
| SCHEMBL1190071 | 0.87 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1KMT2AHDAC1 | |
| SCHEMBL1190069 | 0.87 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1KMT2AHDAC1 | |
| SCHEMBL1189825 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1POLBL3MBTL1 | |
| SCHEMBL22645114 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1POLBL3MBTL1 | |
| SCHEMBL1189823 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1POLBL3MBTL1 | |
| SCHEMBL8824515 | 0.84 | CYP1A2 (0.58) | ALDH1A1TDP1POLBL3MBTL1KMT2A | |
| SCHEMBL8824516 | 0.84 | CYP1A2 (0.58) | ALDH1A1TDP1POLBL3MBTL1KMT2A | |
| SCHEMBL9907020 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TSHRTDP1POLBL3MBTL1 | |
| SCHEMBL17537559 | 0.82 | POLB (0.49) | ALDH1A1TSHRTDP1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903267-B | Synthesis method of olefine acid compound containing (tetrahydro) furan substituent | 中国科学院宁波材料技术与工程研究所 | 2023-09-22 | — | — | CN | disclosed |
| US-11319292-B2 | Metabolically stable 5-HMF derivatives for the treatment of hypoxia | KING ABDULAZIZ UNIVERSITY (SA) | 2022-05-03 | — | — | US | disclosed |
| US-11319292-B2 | Metabolically stable 5-HMF derivatives for the treatment of hypoxia | KING ABDULAZIZ UNIVERSITY (SA) | 2022-05-03 | — | — | US | disclosed |
| US-11220475-B2 | Monomers from biomass | NDSU RESEARCH FOUNDATION (US) | 2022-01-11 | — | — | US | disclosed |
| US-20210403434-A1 | METABOLICALLY STABLE 5-HMF DERIVATIVES FOR THE TREATMENT OF HYPOXIA | VIRGINIA COMMONWEALTH UNIVERSITY | 2021-12-30 | — | — | US | disclosed |
| US-20210403434-A1 | METABOLICALLY STABLE 5-HMF DERIVATIVES FOR THE TREATMENT OF HYPOXIA | VIRGINIA COMMONWEALTH UNIVERSITY | 2021-12-30 | — | — | US | disclosed |
| US-20210340109-A1 | METABOLICALLY STABLE 5-HMF DERIVATIVES FOR THE TREATMENT OF HYPOXIA | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-11-04 | — | — | US | disclosed |
| US-20210340109-A1 | METABOLICALLY STABLE 5-HMF DERIVATIVES FOR THE TREATMENT OF HYPOXIA | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-11-04 | — | — | US | disclosed |
| US-11149012-B1 | Metabolically stable 5-HMF derivatives for the treatment of hypoxia | KING ABDULAZIZ UNIVERSITY (SA) | 2021-10-19 | — | — | US | disclosed |
| US-11149012-B1 | Metabolically stable 5-HMF derivatives for the treatment of hypoxia | KING ABDULAZIZ UNIVERSITY (SA) | 2021-10-19 | — | — | US | disclosed |
| US-20170233325-A1 | NOVEL MONOMERS FROM BIOMASS | NDSU RESEARCH FOUNDATION (US) | 2017-08-17 | — | — | US | disclosed |
| US-20170233325-A1 | NOVEL MONOMERS FROM BIOMASS | NDSU RESEARCH FOUNDATION (US) | 2017-08-17 | — | — | US | disclosed |
| US-20170233325-A1 | NOVEL MONOMERS FROM BIOMASS | NDSU RESEARCH FOUNDATION (US) | 2017-08-17 | — | — | US | disclosed |
| EP-3177583-A2 | NOVEL MONOMERS FROM BIOMASS | Sibi, Mukund P. (US) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016022943-A2 | NOVEL MONOMERS FROM BIOMASS | NDSU RESEARCH FOUNDATION (US) | 2016-02-11 | — | — | WO | disclosed |
| WO-2016022943-A2 | NOVEL MONOMERS FROM BIOMASS | NDSU RESEARCH FOUNDATION (US) | 2016-02-11 | — | — | WO | disclosed |
| US-8236972-B2 | Reacting biomass-derived furfural and malonic acid using basic catalysts to form a Knoevenagel product such as 2-(furan-2-ylmethylene)malonic acid, followed by hydrodeoxygenation to branched alkanes, or branched alkene product; biogasoline; cost efficiency | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-08-07 | — | — | US | disclosed |
| US-8236972-B2 | Reacting biomass-derived furfural and malonic acid using basic catalysts to form a Knoevenagel product such as 2-(furan-2-ylmethylene)malonic acid, followed by hydrodeoxygenation to branched alkanes, or branched alkene product; biogasoline; cost efficiency | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-08-07 | — | — | US | disclosed |
| US-20100029926-A1 | MOLECULAR MASS ENHANCEMENT OF BIOLOGICAL FEEDSTOCKS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-02-04 | — | — | US | disclosed |
| US-20100029926-A1 | MOLECULAR MASS ENHANCEMENT OF BIOLOGICAL FEEDSTOCKS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340109-A1 | METABOLICALLY STABLE 5-HMF DERIVATIVES FOR THE TREATMENT OF HYPOXIA | HIF1AN, HMOX2, HIF1A | ALDH1A1 307/4885TSHR 3524/4885TDP1 4058/4885 |
| US-11149012-B1 | Metabolically stable 5-HMF derivatives for the treatment of hypoxia | HIF1AN, HMOX2, HIF1A | ALDH1A1 307/4885TSHR 3524/4885TDP1 4058/4885 |
| US-20170233325-A1 | NOVEL MONOMERS FROM BIOMASS | DCXR, MANBA, PGLS | ALDH1A1 2942/4885TSHR 4881/4885TDP1 2448/4885 |
| US-11319292-B2 | Metabolically stable 5-HMF derivatives for the treatment of hypoxia | HIF1AN, HMOX2, HIF1A | ALDH1A1 307/4885TSHR 3524/4885TDP1 4058/4885 |
| US-20210403434-A1 | METABOLICALLY STABLE 5-HMF DERIVATIVES FOR THE TREATMENT OF HYPOXIA | HIF1AN, HMOX2, HIF1A | ALDH1A1 307/4885TSHR 3524/4885TDP1 4058/4885 |
| US-11220475-B2 | Monomers from biomass | DCXR, MGAM, ALG1 | ALDH1A1 2167/4885TSHR 4880/4885TDP1 1471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.