Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 13/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20148026 | 0.75 | RET (0.56) | CRHR1 | |
| SCHEMBL25504312 | 0.74 | RET (0.54) | CRHR1 | |
| SCHEMBL5748022 | 0.73 | CNR2 (0.48) | CNR2ANO1 | |
| SCHEMBL20069183 | 0.72 | RET (0.45) | CRHR1 | |
| SCHEMBL20069610 | 0.72 | RET (0.54) | CRHR1 | |
| SCHEMBL21474035 | 0.71 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL24406008 | 0.71 | CRHR1 (0.53) | CNR2CRHR1 | |
| SCHEMBL2088153 | 0.70 | CNR2 (0.47) | CNR2 | |
| SCHEMBL20147663 | 0.70 | RET (0.52) | CRHR1 | |
| SCHEMBL20158533 | 0.70 | RET (0.52) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273900-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-09-25 | — | — | US | disclosed |
| US-20100035898-A1 | Organic compounds | NOVARTIS AG (CH) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035898-A1 | Organic compounds | CRH, CRHR1, CRHR2 | CNR2 133/4885CRHR1 2/4885SMO 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.