Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL321500 | 0.89 | HRH3 (0.39) | HRH3POLBDRD3DRD2DRD4 | |
| SCHEMBL321327 | 0.86 | MAPT (0.47) | HRH3DRD3DRD2BCHEALDH1A1 | |
| SCHEMBL320642 | 0.79 | — | — | |
| SCHEMBL13979094 | 0.78 | — | — | |
| Acetic Acid SCHEMBL321021 | 0.78 | NPSR1 (0.41) | DRD3BCHEALDH1A1MAPTCYP1A2 | |
| SCHEMBL330083 | 0.68 | HRH3 (0.68) | HRH3DRD3DRD2BCHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL17710415 | 0.67 | HRH3 (0.65) | HRH3DRD3DRD2BCHEALDH1A1 | |
| Water SCHEMBL28117059 | 0.67 | HRH3 (0.65) | HRH3DRD3DRD2BCHEALDH1A1 | |
| SCHEMBL11795231 | 0.65 | HTR1A (0.53) | HRH3POLBDRD3BCHEALDH1A1 | |
| Hydrogen Peroxide SCHEMBL139780 | 0.65 | CA12 (0.43) | HRH3DRD3DRD2DRD4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329954-B2 | Cyclopropene amine compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-12-11 | — | — | US | claimed |
| US-20120035269-A1 | CYCLOPROPENE AMINE COMPOUNDS | SISLER EDWARD C (US) | 2012-02-09 | — | — | US | claimed |
| EP-2173691-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | North Carolina State University (US) | 2010-04-14 | — | — | EP | claimed |
| US-20090124504-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY | 2009-05-14 | — | — | US | claimed |
| WO-2009002407-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-12-31 | — | — | WO | claimed |
| EP-2173691-B1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | UNIV NORTH CAROLINA STATE (US) | 2013-11-13 | — | — | EP | disclosed |
| EP-2173691-B1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | UNIV NORTH CAROLINA STATE (US) | 2013-11-13 | — | — | EP | disclosed |
| US-20130137575-A1 | CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-05-30 | — | — | US | disclosed |
| US-20130137575-A1 | CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-05-30 | — | — | US | disclosed |
| US-20130137575-A1 | CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-05-30 | — | — | US | disclosed |
| US-8329954-B2 | Cyclopropene amine compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-12-11 | — | — | US | disclosed |
| US-8329954-B2 | Cyclopropene amine compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-12-11 | — | — | US | disclosed |
| US-8093430-B2 | Methods of inhibiting ethylene responses in plants using cyclopropene amine compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093430-B2 | Methods of inhibiting ethylene responses in plants using cyclopropene amine compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093430-B2 | Methods of inhibiting ethylene responses in plants using cyclopropene amine compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-10 | — | — | US | disclosed |
| EP-2173691-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | North Carolina State University (US) | 2010-04-14 | — | — | EP | disclosed |
| US-20090124504-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY | 2009-05-14 | — | — | US | disclosed |
| US-20090124504-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY | 2009-05-14 | — | — | US | disclosed |
| US-20090124504-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY | 2009-05-14 | — | — | US | disclosed |
| WO-2009002407-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035269-A1 | CYCLOPROPENE AMINE COMPOUNDS | PNMT, EDNRB, CNR1 | HRH3 22/4885POLB 2816/4885DRD3 977/4885 |
| US-20130137575-A1 | CYCLOPROPENE AMINE COMPOUNDS | PNMT, EDNRB, CNR1 | HRH3 22/4885POLB 2816/4885DRD3 977/4885 |
| US-20090124504-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | EDNRB, EDNRA, ECE1 | HRH3 56/4885POLB 2819/4885DRD3 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.