SCHEMBL3203282

SCHEMBL3203282

CC(C)(C)NN=C(CC1=CC=CC1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.35
GAA P10253 7/20 0.33
MAPT P10636 7/20 0.33
ALDH1A1 P00352 6/20 0.33
KDM4E B2RXH2 5/20 0.33
TDP1 Q9NUW8 3/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
ATM Q13315 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
HPGD P15428 2/20 0.32
NPC1 O15118 1/20 0.32
HTT P42858 2/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
TP53 P04637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3216417 0.84 ALDH1A1 (0.48) CTSLGAAMAPTALDH1A1KDM4E
SCHEMBL3199462 0.79 RAB9A (0.39) CTSLALDH1A1KDM4EKMT2AMEN1
SCHEMBL3191208 0.78 CTSL (0.34) CTSLGAAMAPTALDH1A1KDM4E
SCHEMBL3204639 0.78 MAPT (0.37) CTSLGAAMAPTALDH1A1KDM4E
SCHEMBL3202927 0.77 KMT2A (0.37) CTSLGAAMAPTALDH1A1KDM4E
SCHEMBL3192602 0.77 CTSL (0.33) CTSLGAAMAPTALDH1A1KDM4E
SCHEMBL3201943 0.76 KMT2A (0.42) CTSLGAAMAPTALDH1A1KDM4E
SCHEMBL3212084 0.76 CTSL (0.34) CTSLGAAMAPTALDH1A1KDM4E
SCHEMBL3207705 0.76 CTSL (0.34) CTSLGAAMAPTALDH1A1KDM4E
SCHEMBL3205901 0.76 ALDH1A1 (0.33) CTSLGAAMAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 CTSL 3382/4885GAA 4642/4885MAPT 2641/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 CTSL 3382/4885GAA 4642/4885MAPT 2641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.