Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211485 | 0.74 | HPGD (0.33) | HPGD | |
| SCHEMBL7008489 | 0.67 | HPGD (0.31) | HPGD | |
| SCHEMBL5253272 | 0.65 | NOTUM (0.35) | HPGD | |
| SCHEMBL10960773 | 0.63 | HPGD (0.31) | HPGD | |
| SCHEMBL7100243 | 0.61 | HPGD (0.36) | HPGD | |
| SCHEMBL4751217 | 0.59 | HPGD (0.30) | HPGD | |
| SCHEMBL2057181 | 0.56 | HPGD (0.37) | HPGD | |
| SCHEMBL3696580 | 0.56 | HPGD (0.44) | HPGD | |
| SCHEMBL30908747 | 0.56 | — | — | |
| SCHEMBL6430846 | 0.55 | SIGMAR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790712-B2 | Substituted [1,4]diazepino[1,2-A]indoles and azepino[1,2-A]indoles as anti-cytokine inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICAL, INC. (US) | 2010-09-07 | — | — | US | disclosed |