Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211485 | 0.74 | HPGD (0.33) | HPGD | |
| SCHEMBL3203392 | 0.67 | HPGD (0.31) | HPGD | |
| SCHEMBL2057181 | 0.63 | HPGD (0.37) | HPGD | |
| SCHEMBL10960773 | 0.57 | HPGD (0.31) | HPGD | |
| SCHEMBL3696580 | 0.56 | HPGD (0.44) | HPGD | |
| SCHEMBL5231220 | 0.55 | HPGD (0.47) | HPGD | |
| SCHEMBL25138589 | 0.55 | HPGD (0.42) | HPGD | |
| SCHEMBL20776999 | 0.55 | NOTUM (0.44) | HPGD | |
| SCHEMBL12320654 | 0.55 | HPGD (0.42) | HPGD | |
| SCHEMBL975897 | 0.55 | MAOA (0.52) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328525-A2 | 2,3,4,5-TETRAHYDRO-1H-[1,4]DIAZEPINO[1,7-A]INDOLE COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-23 | — | — | EP | claimed |
| WO-2001072752-A2 | 2,3,4,5-TETRAHYDRO-1H-[1,4]DIAZEPINO[1,7-a]INDOLE COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-04 | — | — | WO | claimed |