Butyric Acid

Butyric Acid

SCHEMBL3203906

CC(CO)(CO)CO.CCCC(=O)O.CCCC(=O)O.CCCC(=O)O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.65
HDAC3 O15379 1/20 0.65
HDAC1 Q13547 1/20 0.65
HDAC2 Q92769 1/20 0.65
HDAC8 Q9BY41 1/20 0.65
AKR1B1 P15121 1/20 0.44
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 7/20 0.42
PPARD Q03181 7/20 0.42
PPARA Q07869 7/20 0.42
HDAC11 Q96DB2 5/20 0.42
TSHR P16473 4/20 0.42
PTPN1 P18031 3/20 0.42
ALDH1A1 P00352 2/20 0.42
TLR2 O60603 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
FABP4 P15090 2/20 0.42
KMT2A Q03164 2/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
SLC22A8 Q8TCC7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valeric Acid SCHEMBL21834871 0.86 AKR1B1 (0.58) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL8921701 0.85 FFAR3 (0.65) FFAR3HDAC3HDAC1HDAC2HDAC8
Hexanoate SCHEMBL28278682 0.84 AKR1B1 (0.70) AKR1B1GPR84PPARGPPARDPPARA
Deanol SCHEMBL11695057 0.83 FFAR3 (0.62) FFAR3HDAC3HDAC1HDAC2HDAC8
Dodecanoate SCHEMBL2703312 0.82 GPR84 (0.71) AKR1B1GPR84PPARGPPARDPPARA
Dodecanoate SCHEMBL31655611 0.82 GPR84 (0.71) AKR1B1GPR84PPARGPPARDPPARA
Nonanoate SCHEMBL31655600 0.82 GPR84 (0.71) AKR1B1GPR84PPARGPPARDPPARA
Palmitic Acid SCHEMBL2700408 0.82 GPR84 (0.71) AKR1B1GPR84PPARGPPARDPPARA
Stearic Acid SCHEMBL2701962 0.82 GPR84 (0.71) AKR1B1GPR84PPARGPPARDPPARA
Dodecanoate SCHEMBL2701421 0.82 GPR84 (0.71) AKR1B1GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2740497-B1 Medical adhesive compound AESCULAP AG (DE) 2017-12-06 EP disclosed
EP-2740497-A1 Medical adhesive compound Aesculap AG (DE) 2014-06-11 EP disclosed
US-20100035997-A1 KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES BROADLEY KENNETH N 2010-02-11 US disclosed
US-20100029978-A1 RAPIDLY CURING CYANOACRYLATES AS ADHESIVES SWORDS NOELEEN 2010-02-04 US disclosed
US-20060241226-A1 GAP-FILLING CYANOACRYLATE ADHESIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-10-26 US disclosed
US-6617385-B1 Alkylene biscyanoacrylate; addition polymer; ester plasticizer HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035997-A1 KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES KIT, TEKT1, CUTA FFAR3 1843/4885HDAC3 4848/4885HDAC1 4695/4885
US-20100029978-A1 RAPIDLY CURING CYANOACRYLATES AS ADHESIVES ICAM1, ITGA1, ITGA5 FFAR3 2081/4885HDAC3 3583/4885HDAC1 3266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.