Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | F13A1 | P00488 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701625 | 0.93 | KDM4E (0.62) | KDM4EF13A1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10592850 | 0.90 | KDM4E (0.84) | KDM4EF13A1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6329536 | 0.89 | KDM4E (0.70) | KDM4EF13A1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6845394 | 0.89 | KDM4E (0.70) | KDM4EF13A1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3523937 | 0.87 | KDM4E (0.68) | KDM4EF13A1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4864495 | 0.85 | KDM4E (0.66) | KDM4EF13A1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9201902 | 0.84 | KMT2A (0.59) | KDM4EF13A1SMN1; SMN2MAPTHDAC2 | |
| SCHEMBL28050734 | 0.84 | NPC1 (0.59) | KDM4EF13A1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4704007 | 0.84 | KDM4E (0.51) | KDM4EF13A1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10451965 | 0.84 | KDM4E (0.64) | KDM4EF13A1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2010-03-18 | — | — | US | claimed |
| EP-2054465-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2009-05-06 | — | — | EP | claimed |
| WO-2008023170-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2008-02-28 | — | — | WO | claimed |
| US-8530212-B2 | Carbene precursor compound for producing an adhesive surface on a substrate | ISIS INNOVATION LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2010-03-18 | — | — | US | disclosed |
| EP-2054465-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008023170-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| US-6979566-B2 | Method of treatment of viral infection including HIV using water soluble fullerenes—III | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-12-27 | — | — | US | disclosed |
| US-20040044062-A1 | Method of treatment of viral infection including HIV using water soluble fullerenes - III | FRIEDMAN SIMON H (US) | 2004-03-04 | — | — | US | disclosed |
| US-6613771-B2 | Prevent human retroviral reproduction, infections | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-09-02 | — | — | US | disclosed |
| US-20010041801-A1 | Water soluble fullerenes with antiviral activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-11-15 | — | — | US | disclosed |
| US-6204391-B1 | PREVENT REPRODUCTION OF HUMAN RETROVIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-03-20 | — | — | US | disclosed |
| WO-1995019949-A1 | WATER SOLUBLE FULLERENES WITH ANTIVIRAL ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044062-A1 | Method of treatment of viral infection including HIV using water soluble fullerenes - III | CD4, RPP30, CASP3 | KDM4E 4226/4885F13A1 272/4885SMN1; SMN2 901/4885 |
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ITGB2, ITGA2B, ITGB1 | KDM4E 2738/4885F13A1 647/4885SMN1; SMN2 2731/4885 |
| US-20010041801-A1 | Water soluble fullerenes with antiviral activity | ZC3HAV1, RPL35, SARS1 | KDM4E 4258/4885F13A1 2464/4885SMN1; SMN2 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.