SCHEMBL3204297

SCHEMBL3204297

CC(=O)c1cc2ccccc2cc1C1=C(C)C=C(C)C1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.40
KDM4E B2RXH2 3/20 0.40
CA9 Q16790 2/20 0.40
CA12 O43570 1/20 0.40
CYP1A2 P05177 1/20 0.40
NT5E P21589 1/20 0.40
MYC P01106 1/20 0.36
MAOA P21397 3/20 0.35
POLB P06746 4/20 0.34
MEN1 O00255 3/20 0.34
RAB9A P51151 3/20 0.34
KMT2A Q03164 3/20 0.34
NPC1 O15118 2/20 0.34
MAPT P10636 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
USP2 O75604 1/20 0.34
PLA2G1B P04054 1/20 0.34
THRB P10828 1/20 0.34
ALOX12 P18054 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3198317 0.85 LMNA (0.34) KDM4ECA9MYCMEN1RAB9A
SCHEMBL3203284 0.85 CYP2C8 (0.40) MAOBKDM4ECYP1A2MYCMAOA
SCHEMBL3204386 0.78 KDM4E (0.38) MAOBKDM4ECA9CA12CYP1A2
SCHEMBL3212203 0.78 CA12 (0.38) MAOBKDM4ECA9CA12MYC
SCHEMBL3211819 0.71 MAOB (0.42) MAOBKDM4ECA9CA12CYP1A2
SCHEMBL28466533 0.70 KDM4E (0.57) MAOBKDM4ECA9CA12CYP1A2
SCHEMBL28052572 0.70 PTGS2 (0.47) MAOBKDM4ECA9CA12CYP1A2
SCHEMBL3204263 0.70 MAOB (0.41) MAOBKDM4ECA9CA12CYP1A2
SCHEMBL28877956 0.69 GAPDH (0.32) POLBMEN1KMT2AALOX12ALDH1A1
SCHEMBL14781353 0.67 KDM4E (0.50) MAOBKDM4ECA9CA12CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 MAOB 219/4885KDM4E 4084/4885CA9 1718/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 MAOB 219/4885KDM4E 4084/4885CA9 1718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.