Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.90 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.90 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.90 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.90 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.60 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KDM5C | P41229 | 3/20 | 0.53 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL8141952 | 1.00 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL27309703 | 1.00 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL2222412 | 1.00 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL11729884 | 1.00 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL27505704 | 1.00 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL24441 | 1.00 | — | — | |
| Succinic Acid SCHEMBL18689432 | 0.95 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL7980298 | 0.95 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL8442326 | 0.95 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL9639568 | 0.95 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116334626-B | W etching solution with controllable side etching relative to laminated metal and preparation method thereof | 湖北兴福电子材料股份有限公司 | 2025-03-28 | — | — | CN | claimed |
| WO-2024239642-A1 | COMPOSITE WATER-BASED BINDER AND PREPARATION METHOD THEREFOR, AND LITHIUM-ION BATTERY | 深圳市皓飞新型材料有限公司 | 2024-11-28 | — | — | WO | claimed |
| WO-2024207816-A1 | CORE-SHELL TYPE LITHIUM-CONTAINING POLYACRYLIC WATER-BASED ADHESIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳市皓飞新型材料有限公司 | 2024-10-10 | — | — | WO | claimed |
| CN-118440682-A | Preparation method of high-elasticity, scale-inhibiting and thickening integrated fracturing emulsion | 陕西长海油田助剂有限公司 | 2024-08-06 | — | — | CN | claimed |
| WO-2024128570-A1 | METHOD FOR PRODUCING CRYSTALLINE FIBER USING CARBOXYLIC ACID, SULFONIC ACID, PHOSPHORIC ACID, OR ACID SALT DERIVATIVE THEREOF | (주)비에이에너지 | 2024-06-20 | — | — | WO | claimed |
| EP-3921075-B1 | CLEAVABLE MULTI-ALCOHOL-BASED MICROCAPSULES | FIRMENICH & CIE (CH) | 2024-06-12 | — | — | EP | claimed |
| US-11826362-B2 | Composition for enhancing mitochondrial function | MITOCHOLINE LTD (GB) | 2023-11-28 | — | — | US | claimed |
| CN-115553449-B | Fresh-increasing and fresh-keeping additive for seafood-flavored sauce and preparation method thereof | 青岛日辰食品股份有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116849343-A | Preparation of soup stock essence and preparation method thereof | 哈尔滨粒粒香食品股份有限公司 | 2023-10-10 | — | — | CN | claimed |
| US-20230250369-A9 | CLEAVEABLE MULTI-ALCOHOL-BASED MICROCAPSULES | FIRMENICH SA (CH) | 2023-08-10 | — | — | US | claimed |
| CN-103520051-A | Hair and body shampoo | LIUZHOU LMZ CO LTD | 2014-01-22 | — | — | CN | claimed |
| WO-2012167243-A1 | COMPOSITIONS AND METHODS OF TREATMENT FOR OBESITY | B & P COMPANY, INC. (US) | 2012-12-06 | — | — | WO | claimed |
| CN-102603511-A | Method for producing anhydrous sodium succinate | BAODING WAY CHEIN FOOD IND CO LTD | 2012-07-25 | — | — | CN | claimed |
| CN-101564652-B | Preparation method of nanofiltration membrane by particle packing method | UNIV BEIJING CHEMICAL | 2011-08-10 | — | — | CN | claimed |
| CN-101564652-A | Preparation method of nanofiltration membrane by particle packing method | UNIV BEIJING CHEMICAL (CN) | 2009-10-28 | — | — | CN | claimed |
| CN-100398698-C | Method for preparing anti-corrosion film on metal surface | UNIV BEIJING CHEMICAL (CN) | 2008-07-02 | — | — | CN | claimed |
| CN-1869288-A | Method for preparing anti-corrosion film on metal surface | BEIJING UNIV OF CHEMICAL TECHN (CN) | 2006-11-29 | — | — | CN | claimed |
| CN-1073379-C | Nutritious soy sauce powder | ZHAO HAIZHEN (CN) | 2001-10-24 | — | — | CN | claimed |
| CN-1223091-A | Nutritious soy sauce powder | ZHAO HAIZHEN (CN) | 1999-07-21 | — | — | CN | claimed |
| US-5500668-A | INK JET PRINTING | XEROX CORPORATION (US) | 1996-03-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11826362-B2 | Composition for enhancing mitochondrial function | NLN, NDUFAB1, MT-ND2 | LMNA 1220/4885EGLN1 2719/4885ALKBH5 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.