Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.38 |
| ▸ | TDO2 | P48775 | 10/20 | 0.38 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201538 | 0.78 | POLB (0.33) | MEN1KMT2APOLBATMADRA2A | |
| SCHEMBL3199265 | 0.78 | IDO1 (0.33) | IDO1TDO2IDO2CYP1A2CYP3A4 | |
| SCHEMBL3212272 | 0.77 | NCOA3 (0.33) | — | |
| SCHEMBL3201571 | 0.74 | MAPT (0.32) | IDO1TDO2IDO2CYP1A2CYP3A4 | |
| SCHEMBL3684777 | 0.69 | PNMT (0.37) | IDO1TDO2IDO2CYP2D6CHRM2 | |
| Hydrochloric Acid SCHEMBL3210625 | 0.66 | MEN1 (0.36) | IDO1TDO2IDO2MEN1KMT2A | |
| SCHEMBL28856362 | 0.65 | GABRA1 (0.41) | CYP1A2CYP3A4LMNAMEN1KMT2A | |
| SCHEMBL3259812 | 0.65 | MEN1 (0.33) | MEN1KMT2APOLBATM | |
| SCHEMBL3260464 | 0.63 | GPR3 (0.36) | LMNAMEN1KMT2APOLBATM | |
| SCHEMBL3198546 | 0.61 | HTR2A (0.37) | IDO1MEN1KMT2APOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671226-B2 | Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-02 | — | — | US | disclosed |
| EP-1426379-B1 | TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME | SUMITOMO CHEMICAL CO (JP) | 2009-11-11 | — | — | EP | disclosed |