⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319207 | 0.81 | MGLL (0.36) | — | |
| SCHEMBL1777128 | 0.77 | — | — | |
| SCHEMBL23515492 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL1903489 | 0.75 | ALDH1A1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL10975982 | 0.75 | ALDH1A1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL27493048 | 0.75 | PKM (0.33) | — | |
| SCHEMBL1231909 | 0.73 | MGLL (0.40) | — | |
| SCHEMBL9844837 | 0.73 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL13319165 | 0.73 | TSHR (0.37) | — | |
| SCHEMBL5077735 | 0.71 | MAPT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111635321-A | Fluorinating agent and synthetic method thereof | 山东国邦药业有限公司 | 2020-09-08 | — | — | CN | claimed |
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | LANXESS DEUTSCHLAND GMBH (DE) | 2010-02-11 | — | — | US | claimed |
| US-20050085474-A1 | Fluorinating reagents and their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2005-04-21 | — | — | US | claimed |
| EP-1437342-A2 | Fluorinating reactants and process for their preparation | Bayer Chemicals AG (DE) | 2004-07-14 | — | — | EP | claimed |
| CN-85101921-A | Improving one's methods of preparation 7-halogen-7-deoxy-lincomycin and similar compound thereof | — | 1987-01-10 | — | — | CN | claimed |
| CN-111635321-B | Fluorinating agent and synthesis method thereof | 山东国邦药业有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-111635321-A | Fluorinating agent and synthetic method thereof | 山东国邦药业有限公司 | 2020-09-08 | — | — | CN | disclosed |
| CN-109763318-A | One kind having three-dimensional open-framework alkaline nano carbon fiber | 南京工程学院 | 2019-05-17 | — | — | CN | disclosed |
| CN-107652289-A | Substituted tricyclic compound as FGFR inhibitor | 因塞特控股公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-107383009-A | Substituted tricyclic compound as FGFR inhibitor | 因塞特控股公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-104507943-B | Substituted tricyclic compounds as FGFR inhibitors | 因塞特控股公司 | 2017-11-21 | — | — | CN | disclosed |
| US-20120263706-A1 | ENANTIOMERICALLY PURE AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. | 2012-10-18 | — | — | US | disclosed |
| CN-102099016-A | Drug-loaded polymer nanoparticles and methods of making and using the same | BIND BIOSCIENCES INC | 2011-06-15 | — | — | CN | disclosed |
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | LANXESS DEUTSCHLAND GMBH (DE) | 2010-02-11 | — | — | US | disclosed |
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |
| US-20050085474-A1 | Fluorinating reagents and their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2005-04-21 | — | — | US | disclosed |
| EP-1437342-A2 | Fluorinating reactants and process for their preparation | Bayer Chemicals AG (DE) | 2004-07-14 | — | — | EP | disclosed |
| EP-1437342-A2 | Fluorinating reactants and process for their preparation | Bayer Chemicals AG (DE) | 2004-07-14 | — | — | EP | disclosed |