Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393415 | 0.89 | TP53 (0.36) | CES2CES1TSHRCA1CA2 | |
| SCHEMBL199868 | 0.81 | CES2 (0.48) | CES2CES1ALOX15TSHRCA1 | |
| SCHEMBL6162544 | 0.78 | TPMT (0.48) | TSHRRAB9A | |
| SCHEMBL28364182 | 0.78 | MAPT (0.42) | TSHRCA1CA2LMNAKDM4E | |
| SCHEMBL4247526 | 0.78 | CES2 (0.50) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL67959 | 0.78 | CES2 (0.50) | CES2CES1CA1CA2LMNA | |
| SCHEMBL15540018 | 0.78 | TPMT (0.48) | CA1CA2GSK3B | |
| SCHEMBL811028 | 0.78 | ALDH1A1 (0.50) | CES2CES1GSK3BSRD5A2MAPK1 | |
| SCHEMBL3618348 | 0.78 | CA1 (0.52) | TSHRCA1CA2GSK3BL3MBTL1 | |
| SCHEMBL10999100 | 0.78 | TSHR (0.53) | TSHRSRD5A2MAPK1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539144-A | Tetrahydroisoquinoline aryl urea compound and preparation method and application thereof | 蚌埠医学院 | 2022-05-27 | — | — | CN | claimed |
| CN-112441990-A | Bisamide compound containing 3, 4-dichloroisothiazole heterocycle, and preparation method and application thereof | 江西天宇化工有限公司 | 2021-03-05 | — | — | CN | claimed |
| CN-115197113-B | Combretastatin A-4 derivative containing thiourea structure, preparation method and application thereof | 南通大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-115197113-A | Combretastatin A-4 derivative containing thiourea structure, preparation method and application thereof | 南通大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-113368896-B | Catalyst for diflubenzuron synthesis and preparation method of diflubenzuron | 河北威远生物化工有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114539144-A | Tetrahydroisoquinoline aryl urea compound and preparation method and application thereof | 蚌埠医学院 | 2022-05-27 | — | — | CN | disclosed |
| CN-113368896-A | Catalyst for diflubenzuron synthesis and preparation method of diflubenzuron | 河北威远生物化工有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-112441990-A | Bisamide compound containing 3, 4-dichloroisothiazole heterocycle, and preparation method and application thereof | 江西天宇化工有限公司 | 2021-03-05 | — | — | CN | disclosed |
| EP-2208519-B1 | Agent for separating optical isomers | DAICEL CHEM (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-2208519-A1 | Agent for separating optical isomers | Daicel Chemical Industries, Ltd. (JP) | 2010-07-21 | — | — | EP | disclosed |
| EP-1618949-B1 | AGENT FOR SEPARATING OPTICAL ISOMERS | DAICEL CHEM (JP) | 2010-06-16 | — | — | EP | disclosed |
| EP-0108351-B1 | USE OF SUBSTITUTED MALONIC-ACID DERIVATIVES AS PESTICIDES | BAYER AG (DE) | 1987-07-22 | — | — | EP | disclosed |
| EP-0180813-A1 | Chromogenic 4,4-diaryldihydrochinazolones, their preparation and use | BAYER AG (DE) | 1986-05-14 | — | — | EP | disclosed |
| EP-0126235-A1 | Five-membered nitrogen-containing heterocycles, process for their preparation and their use as pesticides | BAYER AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| EP-0109172-A1 | Novel substituted N-phenyl-N'benzoylureas and their use as insecticides and acaricides | THE DOW CHEMICAL COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |
| EP-0108351-A2 | Use of substituted malonic-acid derivatives as pesticides | BAYER AG (DE) | 1984-05-16 | — | — | EP | disclosed |
| EP-0047496-A1 | Sulfonyl ureas, processes for their production, pharmaceutical compositions based on these compounds and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-17 | — | — | EP | disclosed |
| US-4282212-A | Immune-stimulating 1-(N-acylcarbamoyl)-2-cyanoaziridines | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-04 | — | — | US | disclosed |
| US-4150158-A | Oxadiazindione derivatives useful as insecticides | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4061630-A | 7-Substituted-ureido-3-carbamoyloxymethyl cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1977-12-06 | — | — | US | disclosed |