Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3075879 | 0.77 | MAOA (0.42) | MAOAMAOBATMHTR2ACYP2C9 | |
| SCHEMBL8468871 | 0.71 | MAOA (0.48) | MAOAMAOBATMCYP2C9HDAC3 | |
| SCHEMBL446184 | 0.71 | MAOA (0.38) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL329531 | 0.71 | MAOA (0.38) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL329445 | 0.71 | MAOA (0.38) | MAOAMAOBATMCYP2C9HDAC3 | |
| SCHEMBL6678434 | 0.71 | MAOA (0.38) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL3195757 | 0.71 | MAOA (0.38) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL10994314 | 0.70 | MAOA (0.37) | MAOAMAOBATMHTR2A | |
| SCHEMBL10672022 | 0.69 | CA2 (0.37) | MAOAMAOBATMCYP2C9HDAC3 | |
| SCHEMBL5804260 | 0.68 | MAOA (0.35) | MAOAMAOBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537519-B1 | Method for the preparation of fluoro substituted aminobenzodioxoles and -benzodioxanes and intermediates | BAYER AG (DE) | 1997-06-04 | — | — | EP | claimed |
| US-5260460-A | Process for the preparation of fluorine-substituted aminobenzodioxoles and -benzodioxanes and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | claimed |
| EP-0537519-A1 | Method for the preparation of fluoro substituted aminobenzodioxoles and -benzodioxanes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | claimed |
| CN-117534682-A | Monofunctional bio-based benzoxazine monomer with multi-benzodioxole structure and resin | 江苏大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-117534682-A | Monofunctional bio-based benzoxazine monomer with multi-benzodioxole structure and resin | 江苏大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-102858944-B | Delivery of particles | 宝洁公司 | 2016-08-24 | — | — | CN | disclosed |
| EP-2044084-B1 | MTKI QUINAZOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2016-02-17 | — | — | EP | disclosed |
| CN-104955358-A | Kit for coloring hair | UNILEVER NV | 2015-09-30 | — | — | CN | disclosed |
| US-8492377-B2 | MTKI quinazoline derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2013-07-23 | — | — | US | disclosed |
| US-20100029627-A1 | MTKI QUINAZOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2010-02-04 | — | — | US | disclosed |
| EP-2044084-A2 | MTKI QUINAZOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-08 | — | — | EP | disclosed |
| US-5559253-A | Process for the preparation of fluorine-substituted aminobenzodioxles and -benzodioxanes and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |
| US-5260460-A | Process for the preparation of fluorine-substituted aminobenzodioxoles and -benzodioxanes and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |
| US-5260460-A | Process for the preparation of fluorine-substituted aminobenzodioxoles and -benzodioxanes and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |
| US-5260460-A | Process for the preparation of fluorine-substituted aminobenzodioxoles and -benzodioxanes and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |
| EP-0537519-A1 | Method for the preparation of fluoro substituted aminobenzodioxoles and -benzodioxanes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0537519-A1 | Method for the preparation of fluoro substituted aminobenzodioxoles and -benzodioxanes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0537519-A1 | Method for the preparation of fluoro substituted aminobenzodioxoles and -benzodioxanes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |
| US-4155915-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029627-A1 | MTKI QUINAZOLINE DERIVATIVES | NR4A3, NR4A1, NR5A2 | MAOA 2435/4885MAOB 2712/4885ATM 4767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.