Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3075879 | 0.77 | MAOA (0.42) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL329531 | 0.71 | MAOA (0.38) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL3205774 | 0.71 | MAOA (0.38) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL3195757 | 0.71 | MAOA (0.38) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL329445 | 0.71 | MAOA (0.38) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL446184 | 0.71 | MAOA (0.38) | MAOAMAOBATMHDAC3HDAC4 | |
| SCHEMBL8468871 | 0.71 | MAOA (0.48) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL5807470 | 0.71 | MAOA (0.34) | MAOAMAOB | |
| SCHEMBL10994314 | 0.70 | MAOA (0.37) | MAOAMAOBATM | |
| SCHEMBL5804260 | 0.68 | MAOA (0.35) | MAOAMAOBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766898-B2 | Therapeutic compound for pain and synthesis thereof | JANSSEN PHARMACEUTICA NV (BE) | 2020-09-08 | — | — | US | claimed |
| EP-1202628-B1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2004-10-13 | — | — | EP | disclosed |
| EP-1202628-A4 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2002-10-30 | — | — | EP | disclosed |
| EP-1202628-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | Euro-Celtique S.A. (LU) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001011967-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2001-02-22 | — | — | WO | disclosed |
| EP-0322187-A3 | CONDENSATION POLYMER CONTAINING THE RESIDUE OF A BENZODIOXYLMETHINE COMPOUND AND SHAPED ARTICLES PRODUCED THEREFROM | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-08-09 | — | — | EP | disclosed |
| EP-0322187-A2 | Condensation polymer containing the residue of a benzodioxylmethine compound and shaped articles produced therefrom | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-06-28 | — | — | EP | disclosed |
| US-4058607-A | DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES | AIRWICK INDUSTRIES, INC. (US) | 1977-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766898-B2 | Therapeutic compound for pain and synthesis thereof | OPRL1, HCAR3, HDAC3 | MAOA 1983/4885MAOB 1813/4885PARP1 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.