SCHEMBL3205852

SCHEMBL3205852

Nc1c(S(=O)(=O)O)ccc2cccc(O)c12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.57
AURKB Q96GD4 1/20 0.57
NR4A1 P22736 2/20 0.43
CTRB1 P17538 1/20 0.40
CDK2 P24941 3/20 0.40
TTR P02766 2/20 0.40
FABP4 P15090 1/20 0.40
CCNA2 P20248 1/20 0.40
MAPK14 Q16539 1/20 0.40
MPL P40238 1/20 0.39
CTRC Q99895 1/20 0.39
NT5E P21589 1/20 0.38
CYP1A2 P05177 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPK1 P28482 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALOX12 P18054 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1755221 0.86 TTR (0.49) AURKAAURKBNR4A1CTRB1CDK2
SCHEMBL27412761 0.82 AURKA (0.51) AURKAAURKBNR4A1CTRB1CDK2
SCHEMBL28757570 0.82 AURKA (0.51) AURKAAURKBNR4A1CTRB1CDK2
SCHEMBL6472138 0.80 AURKA (0.41) AURKAAURKBCTRB1TTRNT5E
SCHEMBL465006 0.80 CDK2 (0.53) AURKAAURKBNR4A1CDK2TTR
SCHEMBL9464970 0.79 CDK2 (0.46) AURKAAURKBNR4A1CTRB1CDK2
SCHEMBL2161129 0.79 AURKA (0.49) AURKAAURKBNR4A1CDK2TTR
SCHEMBL9614604 0.78 CYP1A2 (0.46) AURKAAURKBCTRB1MPLCTRC
SCHEMBL10354361 0.78 CDK2 (0.51) AURKAAURKBNR4A1CDK2TTR
SCHEMBL3030721 0.77 AURKA (0.53) AURKAAURKBNR4A1CDK2TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101424672-A Tracer and its use method CHINA PETROCHEMICAL CO LTD (CN) 2009-05-06 CN claimed
EP-0041922-B1 PROCESS FOR THE PREPARATION OF AMINO-SUBSTITUTED 1-AMINO-8-HYDROXY-NAPHTHALENE-SULFONIC ACIDS CIBA-GEIGY AG (CH) 1984-10-03 EP claimed
US-11966050-B2 Head-up display apparatus NITTO DENKO CORPORATION (JP) 2024-04-23 US disclosed
US-11933979-B2 Head-up display device NITTO DENKO CORPORATION (JP) 2024-03-19 US disclosed
EP-3699671-B1 HEAD-UP DISPLAY DEVICE NITTO DENKO CORP (JP) 2024-02-07 EP disclosed
EP-4309944-A2 HEAD-UP DISPLAY DEVICE Nitto Denko Corporation (JP) 2024-01-24 EP disclosed
US-11650419-B2 Head-up display apparatus NITTO DENKO CORPORATION (JP) 2023-05-16 US disclosed
US-20230095922-A1 POLARIZING PLATE AND DISPLAY DEVICE Sharp Display Technology Corporation (JP) 2023-03-30 US disclosed
US-11567315-B2 Head-up display device NITTO DENKO CORPORATION (JP) 2023-01-31 US disclosed
CN-110392851-B Polarizing plate 日东电工株式会社 2022-05-17 CN disclosed
CN-109154685-B Alignment layer forming composition 日产化学株式会社 2022-04-19 CN disclosed
EP-0264137-B1 SCARLET MONOAZO COMPOUND HAVING TWO VINYLSULFONE TYPE FIBER REACTIVE GROUPS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-06-12 EP disclosed
US-4485042-A COLORFASTNESS CASSELLA AKTIENGESELLSCHAFT (DE) 1984-11-27 US disclosed
US-4412948-A FOR DYEING CELLULOSE FIBERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-01 US disclosed
EP-0022265-B1 REACTIVE BISAZO DYES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE FOR DYEING CELLULOSE FIBERS AND CELLULOSIC TEXTILES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-12 EP disclosed
EP-0041922-A1 Process for the preparation of amino-substituted 1-amino-8-hydroxy-naphthalene-sulfonic acids CIBA-GEIGY AG (CH) 1981-12-16 EP disclosed
EP-0041922-A1 Process for the preparation of amino-substituted 1-amino-8-hydroxy-naphthalene-sulfonic acids CIBA-GEIGY AG (CH) 1981-12-16 EP disclosed
EP-0022265-A2 Reactive bisazo dyes, a process for their production and their use for dyeing cellulose fibers and cellulosic textiles SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-01-14 EP disclosed
US-4216166-A Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction AMERICAN CYANAMID COMPANY (US) 1980-08-05 US disclosed
US-4033945-A Water-soluble trisazo 8-amino-naphthol-1 dyes CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11567315-B2 Head-up display device DCX, PLAUR, EPHA4 AURKA 1550/4885AURKB 2339/4885NR4A1 553/4885
US-11650419-B2 Head-up display apparatus SUN2, WAPL, HEATR1 AURKA 3215/4885AURKB 3612/4885NR4A1 1422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.