Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599747 | 0.86 | TTR (0.59) | AURKAAURKBTTRCDK2CASP6 | |
| SCHEMBL29545862 | 0.84 | CDK2 (0.50) | AURKAAURKBTTRCDK2G6PD | |
| SCHEMBL635927 | 0.84 | CDK2 (0.61) | AURKAAURKBCDK2G6PDCASP7 | |
| SCHEMBL565103 | 0.84 | CDK2 (0.50) | AURKAAURKBTTRCDK2G6PD | |
| SCHEMBL9359459 | 0.81 | CDK2 (0.47) | AURKAAURKBTTRCDK2G6PD | |
| SCHEMBL10881024 | 0.80 | AURKA (0.46) | AURKAAURKBTTRCASP7ALDH1A1 | |
| SCHEMBL32077 | 0.80 | TTR (0.64) | AURKAAURKBTTRCDK2ALDH1A1 | |
| SCHEMBL8074354 | 0.79 | AURKA (0.58) | AURKAAURKBTTRCDK2ALDH1A1 | |
| SCHEMBL9808016 | 0.79 | TTR (0.62) | AURKAAURKBTTRCDK2ALDH1A1 | |
| SCHEMBL7569306 | 0.78 | TTR (0.52) | AURKAAURKBTTRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7740913-B2 | Coating a substrate with a maleic anhydride-styrene or maleic anhydride 1-alkene copolymer which has been hydrolyzed and reacted with 3-amino-4-hydroxybenzenesulfonic acid; especially for protecting carpeting, upholstery fabric, wool or other textiles from coffee and acid dye stains | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-22 | — | — | US | claimed |
| US-20090221200-A1 | Coating a substrate with a maleic anhydride-styrene or maleic anhydride 1-alkene copolymer which has been hydrolyzed and reacted with 3-amino-4-hydroxybenzenesulfonic acid; especially for protecting carpeting, upholstery fabric, wool or other textiles from coffee and acid dye stains | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-09-03 | — | — | US | claimed |
| WO-2008016450-A1 | COPOLYMERS FOR STAIN RESISTANCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-02-07 | — | — | WO | claimed |
| US-20080022463-A1 | from reaction of a primary or secondary amine (an amino-hydroxyaromatic acid) with an alkene/maleic anhydride or an alpha olefin/maleic anhydride copolymer; for coffee or a red acid dye stain (KoolAid) on polyamide carpeting, upholstery fabric, wool and other textiles; maleic anhydride-styrene copolymer | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-01-31 | — | — | US | claimed |
| US-5223373-A | Positive working photosensitive composition and photosensitive electrodeposition composition prepared therefrom | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1993-06-29 | — | — | US | claimed |
| US-20240167922-A1 | TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD | KYOTO UNIVERSITY (JP) | 2024-05-23 | — | — | US | disclosed |
| EP-4306927-A1 | TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD | Kyoto University (JP) | 2024-01-17 | — | — | EP | disclosed |
| US-20230126240-A1 | COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20230126240-A1 | COLORING COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
| WO-2022191336-A1 | TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD | 国立大学法人京都大学 | 2022-09-15 | — | — | WO | disclosed |
| CN-114539243-A | Novel deuterium-substituted Positron Emission Tomography (PET) imaging agents and their pharmacological use | 五一一制药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-112203673-A | Mixed mu opioid receptor and neuropeptide FF receptor binding molecules, methods of making, and uses in therapy | 国家科学研究中心 | 2021-01-08 | — | — | CN | disclosed |
| US-4886549-A | Vat dye and sulfur dye compositions | CIBA-GEIEGY CORPORATION (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0282814-A2 | Colour photographic recording material for the diffusion transfer process | Agfa-Gevaert AG (DE) | 1988-09-21 | — | — | EP | disclosed |
| EP-0140252-B1 | POLYAZO DYES | BASF Aktiengesellschaft (DE) | 1988-01-07 | — | — | EP | disclosed |
| EP-0241414-A2 | Process for the preparation of 1:2 metal complex azo dyes | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | disclosed |
| US-4617256-A | NONDIFFUSING YELLOW COUPLER; STABILITY | AGFA GEVAERT AKTIENGESELLSCHAFT (DE) | 1986-10-14 | — | — | US | disclosed |
| EP-0055694-B1 | PROCESS FOR DYEING OR PRINTING CELLULOSIC MATERIALS AND MIXED CELLULOSE/POLYESTER FABRICS | CIBA-GEIGY AG (CH) | 1986-06-04 | — | — | EP | disclosed |
| US-4519805-A | Vat dye and sulfur dye compositions | CIBA GEIGY CORPORATION (US) | 1985-05-28 | — | — | US | disclosed |
| EP-0055694-A2 | Process for dyeing or printing cellulosic materials and mixed cellulose/polyester fabrics | CIBA-GEIGY AG (CH) | 1982-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240167922-A1 | TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD | TST, TTR, ALB | AURKA 4442/4885AURKB 4130/4885TTR 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.