SCHEMBL3205909

SCHEMBL3205909

CCC(N)N(C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 6/20 0.44
SLC6A4 P31645 6/20 0.44
HTR2A P28223 1/20 0.40
HRH1 P35367 1/20 0.40
AOC3 Q16853 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 2/20 0.36
GLA P06280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4595133 0.82 HTR2A (0.43) SLC6A2SLC6A4HTR2AHRH1AOC3
SCHEMBL6979080 0.81 SLC6A2 (0.43) SLC6A2SLC6A4HTR2AHRH1AOC3
SCHEMBL8020762 0.80 ALDH1A1 (0.38) SLC6A2SLC6A4HTR2AHRH1AOC3
Hydrochloric Acid SCHEMBL11154625 0.78 SLC6A2 (0.50) SLC6A2SLC6A4HTR2AAOC3KDM4E
SCHEMBL7641118 0.77 CSNK1E (0.46) SLC6A2SLC6A4HTR2AALDH1A1
SCHEMBL20878111 0.77 SLC6A2 (0.43) SLC6A2SLC6A4HTR2AHRH1AOC3
SCHEMBL8649207 0.77 MAPT (0.40) SLC6A2SLC6A4HTR2AHRH1TDP1
SCHEMBL95074 0.76 TSHR (0.42) SLC6A2SLC6A4HTR2AHRH1ALDH1A1
Hydrochloric Acid SCHEMBL8619260 0.75 MAPT (0.39) SLC6A2SLC6A4HTR2AHRH1AOC3
SCHEMBL11358492 0.75 SLC6A2 (0.44) SLC6A2SLC6A4AOC3ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5710012-A DETECTION OF CHOLESTEROL BY RELEASE OF HYDROGEN PEROXIDE ACTIMED LABORATORIES, INC. (US) 1998-01-20 US claimed
US-7678850-B2 Pigment dispersions containing aminated acrylic macromonomer dispersant E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-16 US disclosed
US-20090012231-A1 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY 2009-01-08 US disclosed
EP-1966335-A2 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-09-10 EP disclosed
WO-2007070724-A2 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-06-21 WO disclosed
US-20070142546-A1 Pigment dispersions containing aminated acrylic macromonomer dispersant AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2007-06-21 US disclosed
US-5710012-A DETECTION OF CHOLESTEROL BY RELEASE OF HYDROGEN PEROXIDE ACTIMED LABORATORIES, INC. (US) 1998-01-20 US disclosed
US-5518891-A SUBSTITUTED ANILINES, HYDRAZONES OR 4-AMINOANTIPYRINES ACTIMED LABORATORIES, INC. (US) 1996-05-21 US disclosed
US-4268439-A Basic azo dyestuffs having benzylammoniumamine substituent in the coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-05-19 US disclosed