Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39602 | 0.88 | ALDH1A1 (0.36) | TSHRALDH1A1GRIN1GRIN2AGRIN2D | |
| Aniline SCHEMBL4439642 | 0.86 | ALDH1A1 (0.45) | TSHRALDH1A1SLC6A2SLC6A4GRIN1 | |
| Diphenylamine SCHEMBL4439637 | 0.85 | MEN1 (0.46) | TSHRALDH1A1SLC6A2NPY5RMEN1 | |
| SCHEMBL6887995 | 0.84 | ALDH1A1 (0.35) | TSHRALDH1A1GLASLC6A2SLC6A4 | |
| SCHEMBL11728189 | 0.83 | MEN1 (0.49) | TSHRALDH1A1SLC6A2NPY5RMEN1 | |
| SCHEMBL27152602 | 0.83 | SLC6A2 (0.40) | TSHRALDH1A1GLASLC6A2SLC6A4 | |
| SCHEMBL2545305 | 0.80 | TSHR (0.41) | TSHRALDH1A1GLASLC6A2SLC6A4 | |
| SCHEMBL10349465 | 0.80 | SLC6A2 (0.53) | SLC6A2SLC6A4HTR2AADRA2BADRA2C | |
| SCHEMBL2258445 | 0.79 | SIGMAR1 (0.39) | SLC6A2SLC6A4HTR2AADRA2BADRA2C | |
| SCHEMBL24865127 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1GLAGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10294250-B2 | Organoaminosilanes and methods for making same | VERSUM MATERIALS US, LLC (US) | 2019-05-21 | — | — | US | disclosed |
| EP-2940021-B1 | CYANINE DYE COMPOUND AND PREPARATION METHOD THEREFOR, AND DUAL-FUNCTION AGENT FOR PHOTODYNAMIC THERAPY AND PREPARATION METHOD THEREFOR | ZHEJIANG HISUN PHARM CO LTD (CN) | 2018-06-13 | — | — | EP | disclosed |
| EP-3216786-A1 | PYRIMIDINE OR PYRIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | Shanghai Shaletech Technology Co., Ltd. (CN) | 2017-09-13 | — | — | EP | disclosed |
| US-9758534-B2 | Organoaminosilanes and methods for making same | VERSUM MATERIALS US, LLC (US) | 2017-09-12 | — | — | US | disclosed |
| US-20170204120-A1 | Organoaminosilanes and Methods for Making Same | VERSUM MATERIALS US, LLC (US) | 2017-07-20 | — | — | US | disclosed |
| US-20160137777-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2016-05-19 | — | — | US | disclosed |
| US-20130172524-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8362252-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| EP-1797082-B1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2010-10-14 | — | — | US | disclosed |
| US-7777038-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-08-17 | — | — | US | disclosed |
| US-20090326008-A1 | NF-kappa B Inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| US-7390924-B2 | Terphenyl derivatives, preparation thereof, compositions containing same | SANOFI-AVENTIS (FR) | 2008-06-24 | — | — | US | disclosed |
| US-20070179173-A1 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
| US-6815183-B1 | Plasmodium sp. chitinase | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2004-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204120-A1 | Organoaminosilanes and Methods for Making Same | DDAH1, IDUA, DDT | TSHR 3989/4885ALDH1A1 418/4885GLA 1279/4885 |
| US-20090326008-A1 | NF-kappa B Inhibitor | NFKBIA, NFKB2, IKBKB | TSHR 3439/4885ALDH1A1 2948/4885GLA 4247/4885 |
| US-20070179173-A1 | Carbostyril compound | GTF2F1, F3, GTF2F2 | TSHR 110/4885ALDH1A1 2458/4885GLA 4101/4885 |
| US-10294250-B2 | Organoaminosilanes and methods for making same | DDAH1, IDUA, DDT | TSHR 3989/4885ALDH1A1 418/4885GLA 1279/4885 |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | GTF2F1, F3, GTF2F2 | TSHR 110/4885ALDH1A1 2458/4885GLA 4101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.