Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phthalic Anhydride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Anhydride SCHEMBL10714375 | 0.91 | TDP1 (0.58) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Phthalic Anhydride SCHEMBL25294110 | 0.90 | TDP1 (0.39) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Phthalic Anhydride SCHEMBL11354692 | 0.89 | ALDH1A1 (0.39) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Phthalic Anhydride SCHEMBL11688988 | 0.85 | TDP1 (0.38) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Maleic Anhydride SCHEMBL1042382 | 0.85 | TDP1 (0.48) | TDP1TSHR | |
| Phthalic Anhydride SCHEMBL3820747 | 0.83 | TDP1 (0.58) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Maleic Anhydride SCHEMBL28887980 | 0.81 | TDP1 (0.43) | TDP1 | |
| Phthalic Anhydride SCHEMBL2225304 | 0.81 | TDP1 (0.74) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Phthalic Anhydride SCHEMBL3038497 | 0.80 | ALOX15 (0.58) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Phthalic Anhydride SCHEMBL28903185 | 0.79 | TDP1 (0.70) | TDP1ALOX15ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119409442-B | Reactive asphalt cold-patch material and preparation method thereof | 长春市城建维护集团股份有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119409442-A | Reactive asphalt cold-patch material and preparation method thereof | 长春市城建维护集团股份有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-119409442-B | Reactive asphalt cold-patch material and preparation method thereof | 长春市城建维护集团股份有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119409442-A | Reactive asphalt cold-patch material and preparation method thereof | 长春市城建维护集团股份有限公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-3786198-A1 | COMPOSITION HAVING EXCELLENT CURABILITY | Kuraray Co., Ltd. (JP) | 2021-03-03 | — | — | EP | disclosed |
| US-7792398-B2 | Optically controlled optical-path-switching-type data distribution apparatus and distribution method | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2010-09-07 | — | — | US | disclosed |
| US-7301686-B2 | Optically controlled optical-path-switching apparatus, and method of switching optical paths | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-20070159682-A1 | Optically controlled optical-path-switching-type data distribution apparatus and distribution method | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070104417-A1 | Optically controlled optical-path-switching apparatus, and method of switching optical paths | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| US-20010001945-A1 | Apparatus for fabricating thin films | HIRAGA TAKASHI (JP) | 2001-05-31 | — | — | US | disclosed |
| EP-0041128-B1 | PROCESS FOR PREPARATION OF MODIFIED AROMATIC HYDROCARBON RESIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1984-03-14 | — | — | EP | disclosed |
| US-4371675-A | WITH UNSATURATED POLYBASIC CARBOXYLIC ACIDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1983-02-01 | — | — | US | disclosed |
| EP-0041128-A2 | Process for preparation of modified aromatic hydrocarbon resin | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1981-12-09 | — | — | EP | disclosed |
| US-4029615-A | AZO COMPOUNDS | PENNWALT CORPORATION (US) | 1977-06-14 | — | — | US | disclosed |
| US-3993609-A | ACID SENSITIVE AZO PROMOTERS | PENNWALT CORPORATION (US) | 1976-11-23 | — | — | US | disclosed |