Maleic Anhydride

Maleic Anhydride

SCHEMBL1042382

CC(O)CO.O=C1C=CC(=O)O1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Maleic Anhydride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.48
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Anhydride SCHEMBL28887980 0.96 TDP1 (0.43) TDP1
Maleic Anhydride SCHEMBL28981873 0.92 TDP1 (0.40) TDP1
Maleic Anhydride SCHEMBL7668321 0.86 TRPA1 (0.33) TSHR
Phthalic Anhydride SCHEMBL3206461 0.85 TDP1 (0.48) TDP1TSHR
Adipic Acid SCHEMBL735379 0.85 PTGS1 (0.39) TDP1TSHR
Maleic Anhydride SCHEMBL19638623 0.85 ALDH1A1 (0.35)
Maleic Anhydride SCHEMBL10925044 0.85 CYP3A4 (0.33) TDP1
Maleic Anhydride SCHEMBL4612052 0.83 LMNA (0.45)
Maleic Anhydride SCHEMBL11870012 0.81 TDP1 (0.37) TDP1
Styrene SCHEMBL27968255 0.81 ALDH1A1 (0.44) TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113174126-A High-performance SMC molding compound and preparation method thereof 河北英丽达新材料科技有限公司 2021-07-27 CN claimed
WO-2007098442-A2 CONTROLLED SHRINKAGE ULTRAVIOLET LIGHT RESISTANT MOLDING COMPOUND CONTINENTAL STRUCTURAL PLASTICS (US) 2007-08-30 WO claimed
US-20070197694-A1 CONTROLLED SHRINKAGE ULTRAVIOLET LIGHT RESISTANT MOLDING COMPOUND CONTINENTAL STRUCTURAL PLASTICS 2007-08-23 US claimed
US-20240218117-A1 POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES Visolis, Inc. 2024-07-04 US disclosed
CN-112876378-B Polymers prepared from mevalonic lactones and derivatives 维索利斯有限公司 2023-08-15 CN disclosed
CN-114206483-A Hollow fiber membrane 路博润先进材料公司 2022-03-18 CN disclosed
CN-113174126-A High-performance SMC molding compound and preparation method thereof 河北英丽达新材料科技有限公司 2021-07-27 CN disclosed
CN-112876378-A Polymers prepared from mevalonolactone and derivatives 维索利斯有限公司 2021-06-01 CN disclosed
CN-112334216-A Flat porous PVC film 路博润先进材料公司 2021-02-05 CN disclosed
US-20200369827-A1 POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES Visolis, Inc. 2020-11-26 US disclosed
EP-3217972-B1 POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES VISOLIS INC (US) 2020-06-24 EP disclosed
US-5811478-A THERMOSETTING RESIN BLENDED WITH A COPOLYMERIZABLE OLEFIN MONOMER, AN ANTIOXIDANT AND AN EPOXY COMPOUND UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-09-22 US disclosed
EP-0351831-B1 Improved polyester compositions UNION CARBIDE CHEM PLASTIC (US) 1994-11-30 EP disclosed
US-5166291-A Unsaturated polyester and styrene with additives of polyvinyl acetate, polymethyl methacrylate and polyurethanes with lactam additives UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-11-24 US disclosed
EP-0351831-A2 Improved polyester compositions UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (a New York corporation) (US) 1990-01-24 EP disclosed
US-4678711-A SELF-CROSSLINKING ACRYLIC PRIMER UNION CARBIDE CORPORATION (US) 1987-07-07 US disclosed
US-4222929-A Low-shrink in-mold coating THE GENERAL TIRE & RUBBER COMPANY (US) 1980-09-16 US disclosed
US-4189517-A UNSATURATED POLYESTER, SATURATED POLYESTER, DIISOCYANATE, CROSSLINKING POLYOL, POLYVINYL ACETATE THE GENERAL TIRE & RUBBER COMPANY (US) 1980-02-19 US disclosed
US-4040923-A COATINGS, MOLDINGS EASTMAN KODAK COMPANY (US) 1977-08-09 US disclosed
US-3959209-A Curable solid polyester resins KOPPERS COMPANY, INC. (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200369827-A1 POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES COASY, FASN, GGPS1 TDP1 3282/4885TSHR 4819/4885
US-20240218117-A1 POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES COASY, FASN, GGPS1 TDP1 3282/4885TSHR 4819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.