Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145163 | 0.88 | TSHR (0.45) | TSHRALDH1A1THRB | |
| SCHEMBL4437900 | 0.85 | TSHR (0.37) | TSHRTHRB | |
| SCHEMBL360524 | 0.84 | TSHR (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL28371093 | 0.81 | TSHR (0.40) | TSHRALDH1A1THRB | |
| SCHEMBL28266442 | 0.79 | THRB (0.43) | TSHRALDH1A1THRB | |
| SCHEMBL395895 | 0.78 | TSHR (0.40) | TSHRALDH1A1THRB | |
| SCHEMBL27875083 | 0.77 | ALDH1A1 (0.62) | TSHRALDH1A1THRB | |
| SCHEMBL4445988 | 0.76 | THRB (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL2958964 | 0.75 | TSHR (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL3206542 | 0.75 | TSHR (0.35) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041909-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | disclosed |