Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CPB1 | P15086 | 3/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23038435 | 0.77 | CPB2 (0.49) | CPB2CYP2C19CYP2C9TSHRMTOR | |
| SCHEMBL3255442 | 0.77 | CYP2C9 (0.41) | CPB2CYP2C19CYP2C9TSHRMTOR | |
| SCHEMBL16645474 | 0.73 | GRIA4 (0.36) | IRAK4HTTKDM4E | |
| SCHEMBL24501678 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL9460338 | 0.71 | CPB2 (0.41) | CPB2CYP2C19CYP2C9TSHRMTOR | |
| SCHEMBL9953903 | 0.70 | CPB2 (0.43) | CPB2CYP2C19CYP2C9TSHRMTOR | |
| SCHEMBL16150119 | 0.69 | KDM4E (0.41) | TSHRTDP1KMT2ASMN1; SMN2HTT | |
| SCHEMBL10065632 | 0.69 | KMT2A (0.33) | KMT2ASMN1; SMN2 | |
| SCHEMBL21690268 | 0.69 | KMT2A (0.33) | KMT2ASMN1; SMN2 | |
| SCHEMBL6240870 | 0.69 | KMT2A (0.33) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9779901-B2 | High temperature material compositions for high temperature thermal cutoff devices | THERM-O-DISC, INCORPORATED (US) | 2017-10-03 | — | — | US | disclosed |
| US-20150162153-A1 | HIGH TEMPERATURE MATERIAL COMPOSITIONS FOR HIGH TEMPERATURE THERMAL CUTOFF DEVICES | THERM-O-DISC, INCORPORATED (US) | 2015-06-11 | — | — | US | disclosed |
| US-8961832-B2 | High temperature material compositions for high temperature thermal cutoff devices | THERM-O-DISC, INCORPORATED (US) | 2015-02-24 | — | — | US | disclosed |
| US-20120121795-A1 | HIGH TEMPERATURE MATERIAL COMPOSITIONS FOR HIGH TEMPERATURE THERMAL CUTOFF DEVICES | THERM-O-DISC, INCORPORATED (US) | 2012-05-17 | — | — | US | disclosed |
| US-20100033295-A1 | HIGH TEMPERATURE THERMAL CUTOFF DEVICE | THERM-O-DISC, INCORPORATED (US) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121795-A1 | HIGH TEMPERATURE MATERIAL COMPOSITIONS FOR HIGH TEMPERATURE THERMAL CUTOFF DEVICES | HTT, HTR1A, TPH1 | CPB2 3725/4885CYP2C19 1336/4885CYP2C9 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.