Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
| ▸ | ELOC | Q15369 | 1/20 | 0.35 |
| ▸ | ELOB | Q15370 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116056 | 0.85 | CES2 (0.43) | TSHRCES2CES1LMNAPTGS2 | |
| SCHEMBL81262 | 0.82 | CES1 (0.41) | TSHRPRSS1PRSS2PRSS3CES2 | |
| Methylene Chloride SCHEMBL8625445 | 0.79 | ALDH1A1 (0.43) | TSHRCES2CES1LMNAPTGS2 | |
| SCHEMBL10180676 | 0.77 | PGK1 (0.44) | TSHRCES2CES1 | |
| SCHEMBL24854680 | 0.76 | TSHR (0.62) | TSHRLTA4HPRSS1PRSS2PRSS3 | |
| SCHEMBL28849773 | 0.76 | TSHR (0.62) | TSHRLTA4HPRSS1PRSS2PRSS3 | |
| SCHEMBL24854649 | 0.76 | TSHR (0.62) | TSHRLTA4HPRSS1PRSS2PRSS3 | |
| SCHEMBL10782051 | 0.75 | CES2 (0.54) | TSHRCES2CES1PTGS2NPC1 | |
| SCHEMBL10783782 | 0.75 | CES2 (0.54) | TSHRCES2CES1LMNAPTGS2 | |
| SCHEMBL10187827 | 0.75 | CES2 (0.36) | TSHRCES2CES1PTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530212-B2 | Carbene precursor compound for producing an adhesive surface on a substrate | ISIS INNOVATION LIMITED (GB) | 2013-09-10 | — | — | US | claimed |
| CN-101558106-B | Control of surface properties by chemical modification | ISIS INNOVATION | 2012-10-17 | — | — | CN | claimed |
| EP-2054465-B1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION (GB) | 2012-07-11 | — | — | EP | claimed |
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2010-03-18 | — | — | US | claimed |
| CN-101558106-A | Control of surface properties by chemical modification | ISIS INNOVATION (GB) | 2009-10-14 | — | — | CN | claimed |
| US-8530212-B2 | Carbene precursor compound for producing an adhesive surface on a substrate | ISIS INNOVATION LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| US-8530212-B2 | Carbene precursor compound for producing an adhesive surface on a substrate | ISIS INNOVATION LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| CN-101558106-B | Control of surface properties by chemical modification | ISIS INNOVATION | 2012-10-17 | — | — | CN | disclosed |
| EP-2054465-B1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION (GB) | 2012-07-11 | — | — | EP | disclosed |
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2010-03-18 | — | — | US | disclosed |
| CN-101558106-A | Control of surface properties by chemical modification | ISIS INNOVATION (GB) | 2009-10-14 | — | — | CN | disclosed |
| EP-2054465-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008023170-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ITGB2, ITGA2B, ITGB1 | TSHR 3419/4885LTA4H 438/4885PRSS1 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.