SCHEMBL3207316

SCHEMBL3207316

CC(=O)c1c(C)cccc1C(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MYC P01106 2/20 0.53
AKR1C3 P42330 2/20 0.50
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
ALDH1A1 P00352 5/20 0.45
HPGD P15428 3/20 0.45
KDM4E B2RXH2 2/20 0.45
HSD17B10 Q99714 2/20 0.45
KMT2A Q03164 2/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NPSR1 Q6W5P4 1/20 0.43
KCNK3 O14649 1/20 0.43
KCNK9 Q9NPC2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1667150 0.91 MYC (0.57) MYCAKR1C3POLBGAAMAPT
SCHEMBL31738885 0.91 MYC (0.57) MYCAKR1C3POLBGAAMAPT
SCHEMBL350625 0.87 MYC (0.62) MYCAKR1C3POLBGAAMAPT
SCHEMBL28931857 0.86 AKR1C3 (0.46) MYCAKR1C3GAAMAPTALDH1A1
SCHEMBL8661694 0.85 AKR1C3 (0.53) MYCAKR1C3POLBGAAMAPT
SCHEMBL29215698 0.85 AKR1C3 (0.59) MYCAKR1C3POLBGAAMAPT
SCHEMBL8547538 0.84 MYC (0.51) MYCAKR1C3POLBGAAMAPT
SCHEMBL8547541 0.84 MYC (0.51) MYCAKR1C3POLBGAAMAPT
SCHEMBL3039645 0.82 ALDH1A1 (0.59) MYCAKR1C3POLBMAPTALDH1A1
SCHEMBL19834641 0.81 AKR1C3 (0.53) MYCAKR1C3POLBGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8809465-B2 Thermoplastic resin pellets and method for preparing same TOYO SEIKAN KAISHA, LTD (JP) 2014-08-19 US disclosed
US-20100048825-A1 THERMOPLASTIC RESIN PELLETS AND METHOD FOR PREPARING SAME TOYO SEIKAN KAISHA, LTD. (JP) 2010-02-25 US disclosed
EP-2130874-A1 THERMOPLASTIC RESIN PELLET AND METHOD FOR PRODUCTION THEREOF Toyo Seikan Kaisha, Ltd. (JP) 2009-12-09 EP disclosed