Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207048 | 1.00 | AQP1 (0.39) | AQP1PRMT5WDR77GSK3AGSK3B | |
| SCHEMBL3216292 | 1.00 | AQP1 (0.39) | AQP1PRMT5WDR77GSK3AGSK3B | |
| SCHEMBL3195075 | 0.88 | HTR1A (0.35) | AQP1PRMT5WDR77GSK3AGSK3B | |
| SCHEMBL3209927 | 0.88 | HTR1A (0.35) | AQP1PRMT5WDR77GSK3AGSK3B | |
| SCHEMBL3218181 | 0.88 | HTR1A (0.35) | AQP1PRMT5WDR77GSK3AGSK3B | |
| SCHEMBL3207403 | 0.81 | AQP1 (0.40) | AQP1 | |
| SCHEMBL3195090 | 0.81 | AQP1 (0.40) | AQP1 | |
| SCHEMBL3208760 | 0.81 | AQP1 (0.40) | AQP1 | |
| SCHEMBL3207294 | 0.80 | AQP1 (0.38) | AQP1 | |
| SCHEMBL3216613 | 0.80 | AQP1 (0.38) | AQP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | claimed |
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HTR2C, HTR5A, NPY1R | AQP1 2125/4885PRMT5 2298/4885WDR77 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.