Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8231646 | 0.83 | ACHE (0.56) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| SCHEMBL11288361 | 0.83 | ACHE (0.60) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| SCHEMBL8282401 | 0.81 | ACHE (0.58) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| SCHEMBL27453036 | 0.80 | ACHE (0.52) | ACHEALDH1A1CYP3A4GAA | |
| SCHEMBL1663130 | 0.79 | SLC6A2 (0.46) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL10052083 | 0.79 | CA2 (0.47) | ALDH1A1GAAMEN1ALOX12KMT2A | |
| SCHEMBL5471787 | 0.79 | ACHE (0.56) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| SCHEMBL14394777 | 0.79 | ACHE (0.56) | ACHEALDH1A1CYP3A4L3MBTL1MAPT | |
| SCHEMBL1264360 | 0.79 | HTR2A (0.62) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1990376 | 0.79 | KDM4E (0.56) | ALDH1A1L3MBTL1MAPTTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9298094-B2 | Composition for forming fine pattern and method for forming fined pattern using same | MERCK PATENT GMBH (DE) | 2016-03-29 | — | — | US | disclosed |
| US-20140127478-A1 | COMPOSITION FOR FORMING FINE PATTERN AND METHOD FOR FORMING FINED PATTERN USING SAME | AZ ELECTRONIC MATERIALS USA CORP. | 2014-05-08 | — | — | US | disclosed |
| US-7671080-B2 | 1-benzylindole-2-carboxamide derivatives | N.V. ORGANON (NL) | 2010-03-02 | — | — | US | disclosed |
| US-20080280923-A1 | 1-Benzylindole-2-Carboxamide Derivatives | N.V. ORGANON (NL) | 2008-11-13 | — | — | US | disclosed |
| EP-1940788-A1 | 1-BENZYLINDOLE-2-CARBOXAMIDE DERIVATIVES | N.V. Organon (NL) | 2008-07-09 | — | — | EP | disclosed |
| WO-2006100208-A9 | 1-BENZYLINDOLE-2-CARBOXAMIDE DERIVATIVES | ORGANON NV (NL) | 2007-11-22 | — | — | WO | disclosed |
| WO-2006100208-A1 | 1-BENZYLINDOLE-2-CARBOXAMIDE DERIVATIVES | N.V. ORGANON (NL) | 2006-09-28 | — | — | WO | disclosed |
| US-6545147-B1 | E.g., a bicyclic manganese complex containing a bridging 2,6-bis(1,4,7-triazacyclononan-1-ylmethyl)4-methylphenoxide ligand, two bridging acetate groups and two perchlorate anions | CLARIANT GMBH (DE) | 2003-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280923-A1 | 1-Benzylindole-2-Carboxamide Derivatives | CNR2, CNR1, HTR2C | ACHE 1002/4885ALDH1A1 151/4885CYP3A4 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.