SCHEMBL1264360

SCHEMBL1264360

COc1ccc(OC)c(CBr)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.62
IDO1 P14902 2/20 0.61
ADRA1A P35348 1/20 0.61
TAAR1 Q96RJ0 1/20 0.61
HSD17B10 Q99714 1/20 0.58
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
AOC3 Q16853 1/20 0.54
APLNR P35414 1/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
KMT2A Q03164 1/20 0.48
HTR2C P28335 1/20 0.48
MTNR1A P48039 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8067442 0.88 TUBB4A (0.54) HTR2AIDO1ADRA1ATAAR1HSD17B10
SCHEMBL11248414 0.85 HSD17B10 (0.49) HTR2AIDO1ADRA1ATAAR1HSD17B10
SCHEMBL20489173 0.85 MTNR1A (0.52) HTR2AIDO1ADRA1ATAAR1HSD17B10
SCHEMBL20488495 0.85 HTR2A (0.47) HTR2AIDO1ADRA1ATAAR1HSD17B10
SCHEMBL25308876 0.84 ADRA1A (0.68) HTR2AIDO1ADRA1ATAAR1HSD17B10
SCHEMBL1492044 0.83 APLNR (0.63) HTR2AIDO1ADRA1ATAAR1CA12
SCHEMBL2060421 0.83 HTR2A (0.47) HTR2AIDO1ADRA1ATAAR1HSD17B10
SCHEMBL5252421 0.83 IDO1 (0.66) HTR2AIDO1ADRA1ATAAR1HSD17B10
SCHEMBL3202940 0.82 TACR1 (0.46) HTR2AIDO1ADRA1ATAAR1HTR2C
SCHEMBL7414770 0.82 HTR2A (0.49) HTR2AIDO1ADRA1ATAAR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4013739-B1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE WELLA GERMANY GMBH (DE) 2024-10-02 EP claimed
CN-114787122-A Novel polycondensation synthesis of 2-methoxymethyl-p-phenylenediamine 威娜德国有限责任公司 2022-07-22 CN claimed
EP-4013739-A1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE Wella Germany GmbH (DE) 2022-06-22 EP claimed
CN-112538025-A Preparation method of fluorine-containing compound for hydrophobic surface treatment agent 湖北福力德鞋业有限责任公司 2021-03-23 CN claimed
CN-112321413-A Preparation method of 2, 5-dimethoxy phenylacetic acid 爱斯特(成都)生物制药股份有限公司 2021-02-05 CN claimed
JP-5070400-A None JP disclosed
US-20250243216-A1 CD16A BINDING AGENTS AND USES THEREOF KLEO PHARMACEUTICALS, INC. 2025-07-31 US disclosed
CN-114787122-B Novel fold condensation of 2-methoxymethyl-p-phenylenediamine 威娜德国有限责任公司 2025-03-21 CN disclosed
WO-2025016469-A1 ALKOXY THIOPHENE ACYL ARYLAMINE COMPOUNDS AND USE THEREOF 复旦大学 2025-01-23 WO disclosed
US-12162892-B2 CD16a binding agents and uses thereof KLEO PHARMACEUTICALS, INC. (US) 2024-12-10 US disclosed
EP-4013739-B1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE WELLA GERMANY GMBH (DE) 2024-10-02 EP disclosed
US-20240174589-A1 PHOTOREDOX RADICAL BENZYLATION PROCESS CENTRE NAT RECH SCIENT (FR) 2024-05-30 US disclosed
EP-0009386-B1 2,10-DISUBSTITUTED DIBENZO(B,D)PYRANS AND BENZO(C)QUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF PFIZER INC. (US) 1982-11-17 EP disclosed
US-4347375-A Process for preparing amino acids and esters MERCK & CO., INC. (US) 1982-08-31 US disclosed
EP-0007615-B1 PROCESS FOR PREPARING AMINO ACIDS AND ESTERS MERCK & CO. INC. (US) 1982-06-16 EP disclosed
US-4275220-A N-(BENZYLIDENE OR ALKYLIDENE)-2-AMINOCROTONATE CHEMICAL INTERMEDIATE MERCK & CO., INC. (US) 1981-06-23 US disclosed
US-4206225-A ANALGESICS PFIZER INC. (US) 1980-06-03 US disclosed
EP-0009386-A1 2,10-Disubstituted dibenzo(b,d)pyrans and benzo(c)quinolines and pharmaceutical compositions thereof PFIZER INC. (US) 1980-04-02 EP disclosed
EP-0008657-A1 Alpha-vinyl-alpha-aminoacids and their esters and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1980-03-19 EP disclosed
EP-0007615-A2 Process for preparing amino acids and esters MERCK & CO. INC. (US) 1980-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243216-A1 CD16A BINDING AGENTS AND USES THEREOF FCGR1A, FCGR2A, FCGR3B HTR2A 763/4885IDO1 1888/4885ADRA1A 915/4885
US-12162892-B2 CD16a binding agents and uses thereof FCGR1A, FCGR2A, FCGR3B HTR2A 763/4885IDO1 1888/4885ADRA1A 915/4885
US-20240174589-A1 PHOTOREDOX RADICAL BENZYLATION PROCESS H1-2, H1-3, H1-0 HTR2A 1041/4885IDO1 526/4885ADRA1A 1865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.