SCHEMBL3207666

SCHEMBL3207666

CCCNC(C)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31321062 1.00
SCHEMBL6997820 1.00
Iodide SCHEMBL6053667 0.98 SCN1A (0.41)
SCHEMBL9134952 0.87 SCN9A (0.33)
SCHEMBL11508997 0.86 ALOX15 (0.43)
SCHEMBL12827797 0.86 ALOX15 (0.43)
Beta-Alanine SCHEMBL3202385 0.85 PGR (0.38)
SCHEMBL7066326 0.85 EPHX1 (0.44)
SCHEMBL5183229 0.85 EPHX1 (0.44)
SCHEMBL24709285 0.83 EPHX1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2872490-A1 ANTIPROLIFERATIVE BENZO [B]AZEPIN- 2 - ONES F. Hoffmann-La Roche AG (CH) 2015-05-20 EP claimed
WO-2014009495-A1 ANTIPROLIFERATIVE BENZO [B] AZEPIN- 2 - ONES F. HOFFMANN-LA ROCHE AG (CH) 2014-01-16 WO claimed
EP-4198034-A1 BENZIMIDAZOLE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Tuojie Biotech (Shanghai) Co., Ltd. (CN) 2023-06-21 EP disclosed
EP-3097078-B1 PYRIDINES AND PYRIMIDINES AND USE THEREOF PURDUE PHARMA LP (US) 2022-05-25 EP disclosed
EP-3083606-B1 PYRIMIDINES AND USE THEREOF PURDUE PHARMA LP (US) 2020-10-28 EP disclosed
EP-3677588-A1 MODIFIED OLIGONUCLEOTIDES AND COMPOUND THAT CAN BE USED FOR SYNTHESIZING SAME Guangzhou Ribobio Co., Ltd. (CN) 2020-07-08 EP disclosed
EP-3666274-A1 CARBOXAMIDE DERIVATIVES AND USE THEREOF Purdue Pharma LP (US) 2020-06-17 EP disclosed
EP-3105217-B1 ISOQUINOLINE DERIVATIVES AND USE THEREOF PURDUE PHARMA LP (US) 2019-05-29 EP disclosed
US-10005768-B2 Carboxamide derivatives and use thereof PURDUE PHARMA L.P. (US) 2018-06-26 US disclosed
US-9968589-B2 Method of treating disease by auricular anesthesia of cranial nerves CREWS THOMAS M (US) 2018-05-15 US disclosed
US-9834543-B2 Indazoles and use thereof PURDUE PHARMA L.P. (US) 2017-12-05 US disclosed
US-20120165409-A1 WRINKLE-IMPROVING AGENT SHISEIDO COMPANY, LTD. (JP) 2012-06-28 US disclosed
US-20100035881-A1 WRINKLE-IMPROVING AGENT SHISEIDO COMPANY, LTD. (JP) 2010-02-11 US disclosed
EP-1941861-A1 WRINKLE-IMPROVING AGENT Shiseido Company, Limited (JP) 2008-07-09 EP disclosed
WO-2008045671-A1 MATRIX METALLOPROTEASE INHIBITORS JANSSEN PHARMACEUTICA, N.V. (BE) 2008-04-17 WO disclosed
EP-1880711-A1 PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT AND EXTERNAL COMPOSITION FOR SKIN Shiseido Company, Limited (JP) 2008-01-23 EP disclosed
WO-2007070600-A2 N-(5-MEMBERED HETEROAROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS GENELABS TECHNOLOGIES, INC. (US) 2007-06-21 WO disclosed
EP-1296683-A2 METHODS OF TREATING NEUTROPHIL-RELATED DISEASES WITH TOPICAL ANESTHETICS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2003-04-02 EP disclosed
WO-2002000218-A2 METHODS OF TREATING NEUTROPHIL-RELATED DISEASES WITH TOPICAL ANESTHETICS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2002-01-03 WO disclosed
WO-1994017790-A9 USE OF TOPICAL ANESTHETICS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF BRONCHIAL ASTHMA 1994-09-29 WO disclosed